Sequence of ADCY6_MOUSE
EC Number:4.6.1.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP = 3',5'-cyclic AMP + diphosphate
Other sequences found for EC No. 4.6.1.1
General information:
Sequence
0 MSWFSGLLVP KVDERKTAWG ERNGQKRPRH ANRASGFCAP RYMSCLKNAE PPSPTPAAHT
60 RCPWQDEAFI RRAGPGRGVE LGLRSVALGF DDTEVTTPMG TAEVAPDTSP RSGPSCWHRL
120 VQVFQSKQFR SAKLERLYQR YFFQMNQSSL TLLMAVLVLL MAVLLTFHAA PAQPQPAYVA
180 LLTCASVLFV VLMVVCNRHS FRQDSMWVVS YVVLGILAAV QVGGALAANP HSPSAGLWCP
240 VFFVYITYTL LPIRMRAAVL SGLGLSTLHL ILAWQLNSSD PFLWKQLGAN VVLFLCTNAI
300 GVCTHYPAEV SQRQAFQETR GYIQARLHLQ HENRQQERLL LSVLPQHVAM EMKEDINTKK
360 EDMMFHKIYI QKHDNVSILF ADIEGFTSLA SQCTAQELVM TLNELFARFD KLAAENHCLR
420 IKILGDCYYC VSGLPEARAD HAHCCVEMGV DMIEAISLVR EVTGVNVNMR VGIHSGRVHC
480 GVLGLRKWQF DVWSNDVTLA NHMEAGGGRR IHITRATLQY LNGDYEVEPG RGGERNAYLK
540 EQCIETFLIL GASQKRKEEK AMLAKLQRTR ANSMEGLMPR WVPDRAFSRT KDSKAFRQMG
600 IDDSSKDNRG AQDALNPEDE VDEFLGRAID ARSIDQLRKD HVRRFLLTFQ REDLEKKYSR
660 KVDPRFGAYV ACALLVFCFI CFIQLLVFPY STLILGIYAA IFLLLLVTVL ICAVCSCGSF
720 FPKALQRLSR NIVRSRVHST AVGIFSVLLV FISAIANMFT CNHTPIRTCA ARMLNLTPAD
780 VTACHLQQLN YSLGLDAPLC EGTAPTCSFP EYFVGNVLLS LLASSVFLHI SSIGKLAMTF
840 ILGFTYLVLL LLGPPAAIFD NYDLLLGVHG LASSNETFDG LDCPAVGRVA LKYMTPVILL
900 VFALALYLHA QQVESTARLD FLWKLQATGE KEEMEELQAY NRRLLHNILP KDVAAHFLAR
960 ERRNDELYYQ SCECVAVMFA SIANFSEFYV ELEANNEGVE CLRLLNEIIA DFDEIISEER
1020 FRQLEKIKTI GSTYMAASGL NASTYDQVGR SHITALADYA MRLMEQMKHI NEHSFNNFQM
1080 KIGLNMGPVV AGVIGARKPQ YDIWGNTVNV SSRMDSTGVP DRIQVTTDLY QVLAAKGYQL
1140 ECRGVVKVKG KGEMTTYFLN GGPSS
Download this sequence
in fasta formatDownload all sequences for 4.6.1.1
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
2448
Yoshimura M.,Cooper D.M.F.
Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.
Proc. Natl. Acad. Sci. U.S.A.
89
6716-6720
1992
2449
Premont R.T.,Jacobowitz O.,Iyengar R.
Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation.
Endocrinology
131
2774-2784
1992
2450
Michalski N.,Michel V.,Bahloul A.,Lefevre G.,Barral J.,Yagi H.,Chardenoux S.,Weil D.,Martin P.,Hardelin J.P.,Sato M.,Petit C.
Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.
J. Neurosci.
27
6478-6488
2007
2451
Tang T.,Gao M.H.,Lai N.C.,Firth A.L.,Takahashi T.,Guo T.,Yuan J.X.,Roth D.M.,Hammond H.K.
Adenylyl cyclase type 6 deletion decreases left ventricular function via impaired calcium handling.
Circulation
117
61-69
2008
2452
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
2453
Kwon R.Y.,Temiyasathit S.,Tummala P.,Quah C.C.,Jacobs C.R.
Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells.
FASEB J.
24
2859-2868
2010
2454
Chien C.L.,Wu Y.S.,Lai H.L.,Chen Y.H.,Jiang S.T.,Shih C.M.,Lin S.S.,Chang C.,Chern Y.
Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6).
FEBS Lett.
584
2883-2890
2010
2455
Tang T.,Lai N.C.,Hammond H.K.,Roth D.M.,Yang Y.,Guo T.,Gao M.H.
Adenylyl cyclase 6 deletion reduces left ventricular hypertrophy, dilation, dysfunction, and fibrosis in pressure-overloaded female mice.
J. Am. Coll. Cardiol.
55
1476-1486
2010
2456
Rieg T.,Tang T.,Murray F.,Schroth J.,Insel P.A.,Fenton R.A.,Hammond H.K.,Vallon V.
Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla.
J. Am. Soc. Nephrol.
21
2059-2068
2010
2457
Choi Y.H.,Suzuki A.,Hajarnis S.,Ma Z.,Chapin H.C.,Caplan M.J.,Pontoglio M.,Somlo S.,Igarashi P.
Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.
Proc. Natl. Acad. Sci. U.S.A.
108
10679-10684
2011
2458
Sabbatini M.E.,D'Alecy L.,Lentz S.I.,Tang T.,Williams J.A.
Adenylyl cyclase 6 mediates the action of cyclic AMP-dependent secretagogues in mouse pancreatic exocrine cells via protein kinase A pathway activation.
J. Physiol. (Lond.)
591
3693-3707
2013
2459
Lee K.L.,Hoey D.A.,Spasic M.,Tang T.,Hammond H.K.,Jacobs C.R.
Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo.
FASEB J.
28
1157-1165
2014
2460
Rees S.,Kittikulsuth W.,Roos K.,Strait K.A.,Van Hoek A.,Kohan D.E.
Adenylyl cyclase 6 deficiency ameliorates polycystic kidney disease.
J. Am. Soc. Nephrol.
25
232-237
2014
2461
Fenton R.A.,Murray F.,Dominguez Rieg J.A.,Tang T.,Levi M.,Rieg T.
Renal phosphate wasting in the absence of adenylyl cyclase 6.
J. Am. Soc. Nephrol.
25
2822-2834
2014
2462
Bogard A.S.,Birg A.V.,Ostrom R.S.
Non-raft adenylyl cyclase 2 defines a cAMP signaling compartment that selectively regulates IL-6 expression in airway smooth muscle cells: differential regulation of gene expression by AC isoforms.
Naunyn Schmiedebergs Arch. Pharmacol.
387
329-339
2014
