Sequence of ADCY6_HUMAN
EC Number:4.6.1.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP = 3',5'-cyclic AMP + diphosphate
Other sequences found for EC No. 4.6.1.1
General information:
Sequence
0 MSWFSGLLVP KVDERKTAWG ERNGQKRSRR RGTRAGGFCT PRYMSCLRDA EPPSPTPAGP
60 PRCPWQDDAF IRRGGPGKGK ELGLRAVALG FEDTEVTTTA GGTAEVAPDA VPRSGRSCWR
120 RLVQVFQSKQ FRSAKLERLY QRYFFQMNQS SLTLLMAVLV LLTAVLLAFH AAPARPQPAY
180 VALLACAAAL FVGLMVVCNR HSFRQDSMWV VSYVVLGILA AVQVGGALAA DPRSPSAGLW
240 CPVFFVYIAY TLLPIRMRAA VLSGLGLSTL HLILAWQLNR GDAFLWKQLG ANVLLFLCTN
300 VIGICTHYPA EVSQRQAFQE TRGYIQARLH LQHENRQQER LLLSVLPQHV AMEMKEDINT
360 KKEDMMFHKI YIQKHDNVSI LFADIEGFTS LASQCTAQEL VMTLNELFAR FDKLAAENHC
420 LRIKILGDCY YCVSGLPEAR ADHAHCCVEM GVDMIEAISL VREVTGVNVN MRVGIHSGRV
480 HCGVLGLRKW QFDVWSNDVT LANHMEAGGR AGRIHITRAT LQYLNGDYEV EPGRGGERNA
540 YLKEQHIETF LILGASQKRK EEKAMLAKLQ RTRANSMEGL MPRWVPDRAF SRTKDSKAFR
600 QMGIDDSSKD NRGTQDALNP EDEVDEFLSR AIDARSIDQL RKDHVRRFLL TFQREDLEKK
660 YSRKVDPRFG AYVACALLVF CFICFIQLLI FPHSTLMLGI YASIFLLLLI TVLICAVYSC
720 GSLFPKALQR LSRSIVRSRA HSTAVGIFSV LLVFTSAIAN MFTCNHTPIR SCAARMLNLT
780 PADITACHLQ QLNYSLGLDA PLCEGTMPTC SFPEYFIGNM LLSLLASSVF LHISSIGKLA
840 MIFVLGLIYL VLLLLGPPAT IFDNYDLLLG VHGLASSNET FDGLDCPAAG RVALKYMTPV
900 ILLVFALALY LHAQQVESTA RLDFLWKLQA TGEKEEMEEL QAYNRRLLHN ILPKDVAAHF
960 LARERRNDEL YYQSCECVAV MFASIANFSE FYVELEANNE GVECLRLLNE IIADFDEIIS
1020 EERFRQLEKI KTIGSTYMAA SGLNASTYDQ VGRSHITALA DYAMRLMEQM KHINEHSFNN
1080 FQMKIGLNMG PVVAGVIGAR KPQYDIWGNT VNVSSRMDST GVPDRIQVTT DLYQVLAAKG
1140 YQLECRGVVK VKGKGEMTTY FLNGGPSS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
2435
Wicker R.,Catalan A.G.,Cailleux A.-F.,Starenki D.,Stengel D.,Sarasin A.,Suarez H.G.
Cloning and expression of human adenylyl cyclase type VI in normal thyroid tissues.
Biochim. Biophys. Acta
1493
279-283
2000
2436
Ishikawa K.,Nagase T.,Nakajima D.,Seki N.,Ohira M.,Miyajima N.,Tanaka A.,Kotani H.,Nomura N.,Ohara O.
Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.
DNA Res.
4
307-313
1997
2437
Nakajima D.,Okazaki N.,Yamakawa H.,Kikuno R.,Ohara O.,Nagase T.
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
DNA Res.
9
99-106
2002
2438
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
2439
Hellevuo K.,Yoshimura M.,Kao M.,Hoffman P.L.,Cooper D.M.F.,Tabakoff B.
A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.
Biochem. Biophys. Res. Commun.
192
311-318
1993
2440
Ding Q.,Gros R.,Gray I.D.,Taussig R.,Ferguson S.S.,Feldman R.D.
Raf kinase activation of adenylyl cyclases: isoform-selective regulation.
Mol. Pharmacol.
66
921-928
2004
2441
Zahedi R.P.,Lewandrowski U.,Wiesner J.,Wortelkamp S.,Moebius J.,Schuetz C.,Walter U.,Gambaryan S.,Sickmann A.
Phosphoproteome of resting human platelets.
J. Proteome Res.
7
526-534
2008
2442
Dephoure N.,Zhou C.,Villen J.,Beausoleil S.A.,Bakalarski C.E.,Elledge S.J.,Gygi S.P.
A quantitative atlas of mitotic phosphorylation.
Proc. Natl. Acad. Sci. U.S.A.
105
10762-10767
2008
2443
Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J. Proteome Res.
12
260-271
2013
2444
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
2445
Gros R.,Van Uum S.,Hutchinson-Jaffe A.,Ding Q.,Pickering J.G.,Hegele R.A.,Feldman R.D.
Increased enzyme activity and beta-adrenergic mediated vasodilation in subjects expressing a single-nucleotide variant of human adenylyl cyclase 6.
Arterioscler. Thromb. Vasc. Biol.
27
2657-2663
2007
2446
Gao X.,Sadana R.,Dessauer C.W.,Patel T.B.
Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits.
J. Biol. Chem.
282
294-302
2007
2447
Laquerriere A.,Maluenda J.,Camus A.,Fontenas L.,Dieterich K.,Nolent F.,Zhou J.,Monnier N.,Latour P.,Gentil D.,Heron D.,Desguerres I.,Landrieu P.,Beneteau C.,Delaporte B.,Bellesme C.,Baumann C.,Capri Y.,Goldenberg A.,Lyonnet S.,Bonneau D.,Estournet B.,Quijano-Roy S.,Francannet C.,Odent S.,Saint-Frison M.H.,Sigaudy S.,Figarella-Branger D.,Gelot A.,Mussini J.M.,Lacroix C.,Drouin-Garraud V.,Malinge M.C.,Attie-Bitach T.,Bessieres B.,Bonniere M.,Encha-Razavi F.,Beaufrere A.M.,Khung-Savatovsky S.,Perez M.J.,Vasiljevic A.,Mercier S.,Roume J.,Trestard L.,Saugier-Veber P.,Cordier M.P.,Layet V.,Legendre M.,Vigouroux-Castera A.,Lunardi J.,Bayes M.,Jouk P.S.,Rigonnot L.,Granier M.,Sternberg D.,Warszawski J.,Gut I.,Gonzales M.,Tawk M.,Melki J.
Mutations in CNTNAP1 and ADCY6 are responsible for severe arthrogryposis multiplex congenita with axoglial defects.
Hum. Mol. Genet.
23
2279-2289
2014
