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Sequence of STK19_HUMAN

EC Number:2.7.11.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
non-specific serine/threonine protein kinase
P49842
Homo sapiens
368
40916
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.1

General information:

Sequence
  0 MQKWFSAFDD AIIQRQWRAN PSRGGGGVSF TKEVDTNVAT GAPPRRQRVP GRACPWREPI
 60 RGRRGARPGG GDAGGTPGET VRHCSAPEDP IFRFSSLHSY PFPGTIKSRD MSWKRHHLIP
120 ETFGVKRRRK RGPVESDPLR GEPGSARAAV SELMQLFPRG LFEDALPPIV LRSQVYSLVP
180 DRTVADRQLK ELQEQGEIRI VQLGFDLDAH GIIFTEDYRT RVCDCVLKAC DGRPYAGAVQ
240 KFLASVLPAC GDLSFQQDQM TQTFGFRDSE ITHLVNAGVL TVRDAGSWWL AVPGAGRFIK
300 YFVKGRQAVL SMVRKAKYRE LLLSELLGRR APVVVRLGLT YHVHDLIGAQ LVDCISTTSG
360 TLLRLPET
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
235776
Sargent C.A.,Anderson M.J.,Hsieh S.-L.,Kendall E.,Gomez-Escobar N.,Campbell R.D.
Characterisation of the novel gene G11 lying adjacent to the complement C4A gene in the human major histocompatibility complex.
Hum. Mol. Genet.
3
481-488
1994
235777
Liming S.,Wu L.,Sanlioglu S.,Chen R.,Mendoza A.R.,Dangel A.W.,Carroll M.C.,Zipf W.B.,Yu C.
Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region. Molecular cloning, exon-intron structure, composite retroposon, and breakpoint of gene duplication.
J. Biol. Chem.
269
8466-8476
1994
235778
Xie T.,Rowen L.,Aguado B.,Ahearn M.E.,Madan A.,Qin S.,Campbell R.D.,Hood L.
Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.
Genome Res.
13
2621-2636
2003
235779
Mungall A.J.,Palmer S.A.,Sims S.K.,Edwards C.A.,Ashurst J.L.,Wilming L.,Jones M.C.,Horton R.,Hunt S.E.,Scott C.E.,Gilbert J.G.R.,Clamp M.E.,Bethel G.,Milne S.,Ainscough R.,Almeida J.P.,Ambrose K.D.,Andrews T.D.,Ashwell R.I.S.,Babbage A.K.,Bagguley C.L.,Bailey J.,Banerjee R.,Barker D.J.,Barlow K.F.,Bates K.,Beare D.M.,Beasley H.,Beasley O.,Bird C.P.,Blakey S.E.,Bray-Allen S.,Brook J.,Brown A.J.,Brown J.Y.,Burford D.C.,Burrill W.,Burton J.,Carder C.,Carter N.P.,Chapman J.C.,Clark S.Y.,Clark G.,Clee C.M.,Clegg S.,Cobley V.,Collier R.E.,Collins J.E.,Colman L.K.,Corby N.R.,Coville G.J.,Culley K.M.,Dhami P.,Davies J.,Dunn M.,Earthrowl M.E.,Ellington A.E.,Evans K.A.,Faulkner L.,Francis M.D.,Frankish A.,Frankland J.,French L.,Garner P.,Garnett J.,Ghori M.J.,Gilby L.M.,Gillson C.J.,Glithero R.J.,Grafham D.V.,Grant M.,Gribble S.,Griffiths C.,Griffiths M.N.D.,Hall R.,Halls K.S.,Hammond S.,Harley J.L.,Hart E.A.,Heath P.D.,Heathcott R.,Holmes S.J.,Howden P.J.,Howe K.L.,Howell G.R.,Huckle E.,Humphray S.J.,Humphries M.D.,Hunt A.R.,Johnson C.M.,Joy A.A.,Kay M.,Keenan S.J.,Kimberley A.M.,King A.,Laird G.K.,Langford C.,Lawlor S.,Leongamornlert D.A.,Leversha M.,Lloyd C.R.,Lloyd D.M.,Loveland J.E.,Lovell J.,Martin S.,Mashreghi-Mohammadi M.,Maslen G.L.,Matthews L.,McCann O.T.,McLaren S.J.,McLay K.,McMurray A.,Moore M.J.F.,Mullikin J.C.,Niblett D.,Nickerson T.,Novik K.L.,Oliver K.,Overton-Larty E.K.,Parker A.,Patel R.,Pearce A.V.,Peck A.I.,Phillimore B.J.C.T.,Phillips S.,Plumb R.W.,Porter K.M.,Ramsey Y.,Ranby S.A.,Rice C.M.,Ross M.T.,Searle S.M.,Sehra H.K.,Sheridan E.,Skuce C.D.,Smith S.,Smith M.,Spraggon L.,Squares S.L.,Steward C.A.,Sycamore N.,Tamlyn-Hall G.,Tester J.,Theaker A.J.,Thomas D.W.,Thorpe A.,Tracey A.,Tromans A.,Tubby B.,Wall M.,Wallis J.M.,West A.P.,White S.S.,Whitehead S.L.,Whittaker H.,Wild A.,Willey D.J.,Wilmer T.E.,Wood J.M.,Wray P.W.,Wyatt J.C.,Young L.,Younger R.M.,Bentley D.R.,Coulson A.,Durbin R.M.,Hubbard T.,Sulston J.E.,Dunham I.,Rogers J.,Beck S.
The DNA sequence and analysis of human chromosome 6.
Nature
425
805-811
2003
235781
Ulgiati D.,Townend D.C.,Christiansen F.T.,Dawkins R.L.,Abraham L.J.
Complete sequence of the complement C4 gene from the HLA-A1, B8, C4AQ0, C4B1, DR3 haplotype.
Immunogenetics
43
250-252
1996
235782
Gomez-Escobar N.,Chou C.-F.,Lin W.-W.,Hsieh S.-L.,Campbell R.D.
The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase.
J. Biol. Chem.
273
30954-30960
1998
235783
Wadle A.,Mischo A.,Henrich P.P.,Stenner-Lieven F.,Scherer C.,Imig J.,Petersen G.,Pfreundschuh M.,Renner C.
Characterization of Hap/BAG-1 variants as RP1 binding proteins with antiapoptotic activity.
Int. J. Cancer
117
896-904
2005
235784
Greenman C.,Stephens P.,Smith R.,Dalgliesh G.L.,Hunter C.,Bignell G.,Davies H.,Teague J.,Butler A.,Stevens C.,Edkins S.,O'Meara S.,Vastrik I.,Schmidt E.E.,Avis T.,Barthorpe S.,Bhamra G.,Buck G.,Choudhury B.,Clements J.,Cole J.,Dicks E.,Forbes S.,Gray K.,Halliday K.,Harrison R.,Hills K.,Hinton J.,Jenkinson A.,Jones D.,Menzies A.,Mironenko T.,Perry J.,Raine K.,Richardson D.,Shepherd R.,Small A.,Tofts C.,Varian J.,Webb T.,West S.,Widaa S.,Yates A.,Cahill D.P.,Louis D.N.,Goldstraw P.,Nicholson A.G.,Brasseur F.,Looijenga L.,Weber B.L.,Chiew Y.-E.,DeFazio A.,Greaves M.F.,Green A.R.,Campbell P.,Birney E.,Easton D.F.,Chenevix-Trench G.,Tan M.-H.,Khoo S.K.,Teh B.T.,Yuen S.T.,Leung S.Y.,Wooster R.,Futreal P.A.,Stratton M.R.
Patterns of somatic mutation in human cancer genomes.
Nature
446
153-158
2007
235785
Yin C.,Zhu B.,Zhang T.,Liu T.,Chen S.,Liu Y.,Li X.,Miao X.,Li S.,Mi X.,Zhang J.,Li L.,Wei G.,Xu Z.X.,Gao X.,Huang C.,Wei Z.,Goding C.R.,Wang P.,Deng X.,Cui R.
Pharmacological targeting of STK19 inhibits oncogenic NRAS-driven melanomagenesis.
Cell
176
1113-1127
2019