Sequence of SOMT2_PAPSO
EC Number:2.1.1.117
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
S-adenosyl-L-methionine + (S)-scoulerine = S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine
Other sequences found for EC No. 2.1.1.117
General information:
Sequence
0 MEIHLESQEQ EMKYQSQIWN QICGTVDTSV LRCAIQLGIF DAIHNSGKPM ITLTELSSIV
60 SSPSSSSIEP CNLYRLVRYL SQMDLISIGE CLNEATVSLT GTSKLLLRNQ EKSLIDWVLA
120 ISCEMMVVVW HELSSSVSTP ADEPPIFQKV HGKNALELAG EFPEWNDLIN NAMTSDTSVT
180 KPALIQGCGK ILNGVTSLID VGGGHGATMA YIVEAFPHIK GAVIDLPHVV EAAPERPGVE
240 FISGDIFKSI SNADAVLLKY VLHNWEDTEC VNLLKRCKEA VPADKGKVII MDLVIDDDDN
300 SILTQAKLSL DLTVMNHGGG RERTKEDWRN LIEMSGFSRH EIIPISAMPS IIVAYP
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
233247
Dang T.T.,Facchini P.J.
Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy.
Plant Physiol.
159
618-631
2012
233248
Winzer T.,Gazda V.,He Z.,Kaminski F.,Kern M.,Larson T.R.,Li Y.,Meade F.,Teodor R.,Vaistij F.E.,Walker C.,Bowser T.A.,Graham I.A.
A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine.
Science
336
1704-1708
2012
233249
Park M.R.,Chen X.,Lang D.E.,Ng K.K.S.,Facchini P.J.
Heterodimeric O-methyltransferases involved in the biosynthesis of noscapine in opium poppy.
Plant J.
95
252-267
2018
233250
Li Y.,Smolke C.D.
Engineering biosynthesis of the anticancer alkaloid noscapine in yeast.
Nat. Commun.
7
12137-12137
2016
233251
Li Y.,Li S.,Thodey K.,Trenchard I.,Cravens A.,Smolke C.D.
Complete biosynthesis of noscapine and halogenated alkaloids in yeast.
Proc. Natl. Acad. Sci. U.S.A.
115
0-0
2018
