Sequence of SGPL1_MOUSE

sphinganine-1-phosphate aldolase

Q8R0X7

568

63677

231168

Zhou J.,Saba J.D.

Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast.

Biochem. Biophys. Res. Commun.

242

502-507

1998

231169

Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.

The transcriptional landscape of the mammalian genome.

Science

309

1559-1563

2005

231170

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

231171

Ikeda M.,Kihara A.,Igarashi Y.

Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol.

Biochem. Biophys. Res. Commun.

325

338-343

2004

231172

Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.

A tissue-specific atlas of mouse protein phosphorylation and expression.

Cell

143

1174-1189

2010

231173

Bektas M.,Allende M.L.,Lee B.G.,Chen W.,Amar M.J.,Remaley A.T.,Saba J.D.,Proia R.L.

Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver.

J. Biol. Chem.

285

10880-10889

2010

231174

Allende M.L.,Bektas M.,Lee B.G.,Bonifacino E.,Kang J.,Tuymetova G.,Chen W.,Saba J.D.,Proia R.L.

Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.

J. Biol. Chem.

286

7348-7358

2011

231175

Mitroi D.N.,Karunakaran I.,Graeler M.,Saba J.D.,Ehninger D.,Ledesma M.D.,van Echten-Deckert G.

SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.

Autophagy

13

885-899

2017

231176

Lovric S.,Goncalves S.,Gee H.Y.,Oskouian B.,Srinivas H.,Choi W.I.,Shril S.,Ashraf S.,Tan W.,Rao J.,Airik M.,Schapiro D.,Braun D.A.,Sadowski C.E.,Widmeier E.,Jobst-Schwan T.,Schmidt J.M.,Girik V.,Capitani G.,Suh J.H.,Lachaussee N.,Arrondel C.,Patat J.,Gribouval O.,Furlano M.,Boyer O.,Schmitt A.,Vuiblet V.,Hashmi S.,Wilcken R.,Bernier F.P.,Innes A.M.,Parboosingh J.S.,Lamont R.E.,Midgley J.P.,Wright N.,Majewski J.,Zenker M.,Schaefer F.,Kuss N.,Greil J.,Giese T.,Schwarz K.,Catheline V.,Schanze D.,Franke I.,Sznajer Y.,Truant A.S.,Adams B.,Desir J.,Biemann R.,Pei Y.,Ars E.,Lloberas N.,Madrid A.,Dharnidharka V.R.,Connolly A.M.,Willing M.C.,Cooper M.A.,Lifton R.P.,Simons M.,Riezman H.,Antignac C.,Saba J.D.,Hildebrandt F.

Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency.

J. Clin. Invest.

127

912-928

2017

231177

Prasad R.,Hadjidemetriou I.,Maharaj A.,Meimaridou E.,Buonocore F.,Saleem M.,Hurcombe J.,Bierzynska A.,Barbagelata E.,Bergada I.,Cassinelli H.,Das U.,Krone R.,Hacihamdioglu B.,Sari E.,Yesilkaya E.,Storr H.L.,Clemente M.,Fernandez-Cancio M.,Camats N.,Ram N.,Achermann J.C.,Van Veldhoven P.P.,Guasti L.,Braslavsky D.,Guran T.,Metherell L.A.

Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome.

J. Clin. Invest.

127

942-953

2017

231178

Vienken H.,Mabrouki N.,Grabau K.,Claas R.F.,Rudowski A.,Schoemel N.,Pfeilschifter J.,Luetjohann D.,van Echten-Deckert G.,Meyer Zu Heringdorf D.

Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.

Sci. Rep.

7

43575-43575

2017