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Sequence of PTLH_STRAW

EC Number:1.14.11.35

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
1-deoxypentalenic acid 11beta-hydroxylase
Q82IZ1
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
285
32264
Reaction
1-deoxypentalenate + 2-oxoglutarate + O2 = 1-deoxy-11beta-hydroxypentalenate + succinate + CO2
Other sequences found for EC No. 1.14.11.35

General information:

Sequence
show sequence in fasta format
  0 MTNVTGDYTD CTPLLGDRAA LDSFYEEHGY LFLRNVLDRD LVKTVAEQMR EGLVALGAAD
 60 PHATLEELTI DSFESVDEVA MHDYVKYDAF WNNPSTIKVF EQVFGEPVFV FLSTTIRYYP
120 SQAGSEEPSF HYLTPFHQDG FYIGPNQDFR TFWIPLIRTT RESGGVALAD GSHRRGKRDH
180 VLNESFRRFG HPVRGIPPTE VSEDEHLLHS PMEPGDILLF HAHMCHKSIP NLSKDPRLMR
240 MSMDTRVQPA KSHRGFNAMT PWTESAKDAS KGIMAKITGT PTDVE
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
211314
Omura S.,Ikeda H.,Ishikawa J.,Hanamoto A.,Takahashi C.,Shinose M.,Takahashi Y.,Horikawa H.,Nakazawa H.,Osonoe T.,Kikuchi H.,Shiba T.,Sakaki Y.,Hattori M.
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.
Proc. Natl. Acad. Sci. U.S.A.
98
12215-12220
2001
211315
Ikeda H.,Ishikawa J.,Hanamoto A.,Shinose M.,Kikuchi H.,Shiba T.,Sakaki Y.,Hattori M.,Omura S.
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.
Nat. Biotechnol.
21
526-531
2003
211316
You Z.,Omura S.,Ikeda H.,Cane D.E.
Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlH, a non-heme iron dioxygenase of Streptomyces avermitilis.
J. Am. Chem. Soc.
128
6566-6567
2006
211317
Seo M.J.,Zhu D.,Endo S.,Ikeda H.,Cane D.E.
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
Biochemistry
50
1739-1754
2011
211318
You Z.,Omura S.,Ikeda H.,Cane D.E.,Jogl G.
Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis.
J. Biol. Chem.
282
36552-36560
2007