Sequence of CLR4_CRYNH
EC Number:2.1.1.367
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
[histone H3]-lysine9 N-methyltransferase
J9VWH9
Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
1820
194979
Reaction
S-adenosyl-L-methionine + a [histone H3]-L-lysine9 = S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine9
Other sequences found for EC No. 2.1.1.367
General information:
Sequence
0 MPGARSEAGG VDNPLVLDSS DSDDNLSGLP LNGRVKRIDG NDRSYKKKSL TSMRKSTVVD
60 LTLSDSDEAV ESVNLLPGSS STPDRAAQAG ISDKQPSLRR RPRPFMSIAD SSSPPENQNV
120 ISFLGNHSQE IGELPSPPLV EDRAAPNKME LGGENIAGQN NEANAAQAAV PVSGTPSLTL
180 SSNRPQSVSG AQLVVASSSR SAINSPPRRT PSIPQQSPSS RATPCRSASI ASSRSRPPTP
240 PLPATQSTPV TVSRRLASPI LSPVQAVSSA IISPTIPSIP SHASLSDPTI LSPPSATSAP
300 PNSPIPSTST TVQTPAAALT YARPSTSAAP LPVMPISVTP ATTSPAGPGP SALQSASEAT
360 KSSDQKESPR KTNSKQPSSP SSTHGRWTDT RLFHTPSNLS ATSGKSSAAS SRSKSRAPLS
420 SRAAMSDNVA GPSKTTSVSS THPPSRASPS SLPSQSQRQV HPRPPSRDGV GKREKKSKTL
480 SSGTGQSTPS KFSLPTSDVA SNQKNKSTGL NALPKKPSST PTSSIPQRTS TLATAMAIRP
540 FVRSPTPPSP QSSSEASRSI QTSRGAVKAA QNQDKIHPLS TALSISSHSR EATTKATTLF
600 HTTSSPPSPS QSTSAPTKSH VVWNAQKLGT TVLSSERIHL SRGKSQTSDS VVAPAASQTA
660 ASLSYPAGTS GGAREADKKA VETSFHAGPS SADFEAFVQP STSAIAPTTV RPSVAPPEDA
720 PVLKSGSIIH PLFRAASAIG DQNAFTKTEA VGDVLSQGSK GRASSPRITT TGAVSHLAPH
780 VDLGSKIKPT AAPSLFASGV TTKNVDDQDS AQPQNQTPLP SAISVSSKKN HGSLSKESSI
840 KSAASFISSS STLGDSVSGL GRKSHHKSTQ SMPQSPLPTT NTNNSSGIEV NSWLNPQPFG
900 PSFAASHLSI HAKKKWKERE RGKEREKEKV REKEKAEEEN EQLRQRRIAD LEKLSANLEL
960 YKRRMDVESR TRSIPRADGE TRKRPPSPGI SVSTDAEVRV VKRSKPTWAI APEGGHVAPA
1020 MEKESANVNK KAADAIKINH QPASSYAPAF ATPASPAKAT RTPLSVTAGL GPPVNSSSST
1080 STPSLLSRSI NLGILRDKPK DHMDDDDGDD SAGGLPVRKT GKNGAVEEQV EQVRLDLDDV
1140 SIHGSSPAAP LSIFTSRFRD VSITPSRIQK TLEESDNDVP IQRYAVKVNG KQKAQRSKDK
1200 SYGSESENDV PLNWPSRKGK GRTAPEPQDS SETQRDDDDV NLGSGDGEER PSDDDSIPVP
1260 PAPLFKDRTA HVRQPLQTLF KGGIVAKHSY QRPLAKASAV SPVPSANRPS PAPSAKADLL
1320 PQKRKRRLKK ITSQQWQHIA QNSLSDVDDL LGESSKKRLS PENAEKLGAD LSKLTRPRVF
1380 SIVSRSEPRT KREPIEEDNN EYFTDSDSHT SDVALFSQHP DPPPPPERIR EAKRNFDTRN
1440 IDPWNRQKHT FRSNPALHRA IFEAYIMQST SMEESGGDDI KVTNDVDADG GPPDFEFVYS
1500 DTMLYPDGIP PPELGLGCDC DGPCDPDSET CTCVKRQELY FYDLGLKGFA YDENGKIREN
1560 SASIWECNEL CGCPPECMNR VIQRGRARDT GIEIFKTKEK GWGIRARSFI PSGTYIGSYT
1620 GELIREAESE RRGVTYTAIG RTYVFDLDGW QIRHPPKGLE KIDKRAAELA EAVKMRARAA
1680 MRESQEDAYN AYSVDAFHYG NFTRYFNHSC DPNLAITQAY VKDFHPERPL LVIFTRRDIK
1740 KHEELCISYK GIPDDDDIPS PEPVKKKKGG KGKKQMSKTS ASAHPPEMTA LNSDKGLVEV
1800 KDICRCGAKN CDGRMFNYGP
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
18374
Janbon G.,Ormerod K.L.,Paulet D.,Byrnes E.J. III,Yadav V.,Chatterjee G.,Mullapudi N.,Hon C.-C.,Billmyre R.B.,Brunel F.,Bahn Y.-S.,Chen W.,Chen Y.,Chow E.W.L.,Coppee J.-Y.,Floyd-Averette A.,Gaillardin C.,Gerik K.J.,Goldberg J.,Gonzalez-Hilarion S.,Gujja S.,Hamlin J.L.,Hsueh Y.-P.,Ianiri G.,Jones S.,Kodira C.D.,Kozubowski L.,Lam W.,Marra M.,Mesner L.D.,Mieczkowski P.A.,Moyrand F.,Nielsen K.,Proux C.,Rossignol T.,Schein J.E.,Sun S.,Wollschlaeger C.,Wood I.A.,Zeng Q.,Neuveglise C.,Newlon C.S.,Perfect J.R.,Lodge J.K.,Idnurm A.,Stajich J.E.,Kronstad J.W.,Sanyal K.,Heitman J.,Fraser J.A.,Cuomo C.A.,Dietrich F.S.
Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.
PLoS Genet.
10
0-0
2014
18375
Dumesic P.A.,Homer C.M.,Moresco J.J.,Pack L.R.,Shanle E.K.,Coyle S.M.,Strahl B.D.,Fujimori D.G.,Yates J.R. III,Madhani H.D.
Product binding enforces the genomic specificity of a yeast polycomb repressive complex.
Cell
160
204-218
2015
18376
Brandao F.,Esher S.K.,Ost K.S.,Pianalto K.,Nichols C.B.,Fernandes L.,Bocca A.L.,Pocas-Fonseca M.J.,Alspaugh J.A.
HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence.
Sci. Rep.
8
5209-5209
2018
18377
Catania S.,Dumesic P.A.,Pimentel H.,Nasif A.,Stoddard C.I.,Burke J.E.,Diedrich J.K.,Cook S.,Shea T.,Geinger E.,Lintner R.,Yates J.R. III,Hajkova P.,Narlikar G.J.,Cuomo C.A.,Pritchard J.K.,Madhani H.D.
Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase.
Cell
180
0-0
2020
