Sequence of CPT1_YEAST

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
diacylglycerol cholinephosphotransferase
P17898
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
393
44829
Reaction
CDP-choline + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylcholine
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MGFFIPQSSL GNLKLYKYQS DDRSFLSNHV LRPFWRKFAT IFPLWMAPNL VTLLGFCFII
 60 FNVLTTLYYD PYFDQESPRW TYFSYAIGLF LYQTFDACDG MHARRTGQQG PLGELFDHCI
120 DSINTTLSMI PVCSMTGMGY TYMTIFSQFA ILCSFYLSTW EEYHTHKLYL AEFCGPVEGI
180 IVLCISFIAV GIYGPQTIWH TKVAQFSWQD FVFDVETVHL MYAFCTGALI FNIVTAHTNV
240 VRYYESQSTK SATPSKTAEN ISKAVNGLLP FFAYFSSIFT LVLIQPSFIS LALILSIGFS
300 VAFVVGRMII AHLTMQPFPM VNFPFLIPTI QLVLYAFMVY VLDYQKGSIV SALVWMGLGL
360 TLAIHGMFIN DIIYDITTFL DIYALSIKHP KEI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
18927
Hjelmstad R.H.,Bell R.M.
The sn-1,2-diacylglycerol cholinephosphotransferase of Saccharomyces cerevisiae. Nucleotide sequence, transcriptional mapping, and gene product analysis of the CPT1 gene.
J. Biol. Chem.
265
1755-1764
1990
18928
Mallet L.,Bussereau F.,Jacquet M.
A 43.5 kb segment of yeast chromosome XIV, which contains MFA2, MEP2, CAP/SRV2, NAM9, FKB1/FPR1/RBP1, MOM22 and CPT1, predicts an adenosine deaminase gene and 14 new open reading frames.
Yeast
11
1195-1209
1995
18929
Philippsen P.,Kleine K.,Poehlmann R.,Duesterhoeft A.,Hamberg K.,Hegemann J.H.,Obermaier B.,Urrestarazu L.A.,Aert R.,Albermann K.,Altmann R.,Andre B.,Baladron V.,Ballesta J.P.G.,Becam A.-M.,Beinhauer J.D.,Boskovic J.,Buitrago M.J.,Bussereau F.,Coster F.,Crouzet M.,D'Angelo M.,Dal Pero F.,De Antoni A.,del Rey F.,Doignon F.,Domdey H.,Dubois E.,Fiedler T.A.,Fleig U.,Floeth M.,Fritz C.,Gaillardin C.,Garcia-Cantalejo J.M.,Glansdorff N.,Goffeau A.,Gueldener U.,Herbert C.J.,Heumann K.,Heuss-Neitzel D.,Hilbert H.,Hinni K.,Iraqui Houssaini I.,Jacquet M.,Jimenez A.,Jonniaux J.-L.,Karpfinger-Hartl L.,Lanfranchi G.,Lepingle A.,Levesque H.,Lyck R.,Maftahi M.,Mallet L.,Maurer C.T.C.,Messenguy F.,Mewes H.-W.,Moestl D.,Nasr F.,Nicaud J.-M.,Niedenthal R.K.,Pandolfo D.,Pierard A.,Piravandi E.,Planta R.J.,Pohl T.M.,Purnelle B.,Rebischung C.,Remacha M.A.,Revuelta J.L.,Rinke M.,Saiz J.E.,Sartorello F.,Scherens B.,Sen-Gupta M.,Soler-Mira A.,Urbanus J.H.M.,Valle G.,Van Dyck L.,Verhasselt P.,Vierendeels F.,Vissers S.,Voet M.,Volckaert G.,Wach A.,Wambutt R.,Wedler H.,Zollner A.,Hani J.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
Nature
387
93-98
1997
18930
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
18931
Kuchler K.,Daum G.,Paltauf F.
Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiae.
J. Bacteriol.
165
901-910
1986
18932
Hjelmstad R.H.,Bell R.M.
Mutants of Saccharomyces cerevisiae defective in sn-1,2-diacylglycerol cholinephosphotransferase. Isolation, characterization, and cloning of the CPT1 gene.
J. Biol. Chem.
262
3909-3917
1987
18933
Hjelmstad R.H.,Bell R.M.
sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases in Saccharomyces cerevisiae. Mixed micellar analysis of the CPT1 and EPT1 gene products.
J. Biol. Chem.
266
4357-4365
1991
18934
McGee T.P.,Skinner H.B.,Bankaitis V.A.
Functional redundancy of CDP-ethanolamine and CDP-choline pathway enzymes in phospholipid biosynthesis: ethanolamine-dependent effects on steady-state membrane phospholipid composition in Saccharomyces cerevisiae.
J. Bacteriol.
176
6861-6868
1994
18935
McMaster C.R.,Bell R.M.
Phosphatidylcholine biosynthesis in Saccharomyces cerevisiae. Regulatory insights from studies employing null and chimeric sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases.
J. Biol. Chem.
269
28010-28016
1994
18936
Morash S.C.,McMaster C.R.,Hjelmstad R.H.,Bell R.M.
Studies employing Saccharomyces cerevisiae cpt1 and ept1 null mutants implicate the CPT1 gene in coordinate regulation of phospholipid biosynthesis.
J. Biol. Chem.
269
28769-28776
1994
18937
Leber A.,Hrastnik C.,Daum G.
Phospholipid-synthesizing enzymes in Golgi membranes of the yeast, Saccharomyces cerevisiae.
FEBS Lett.
377
271-274
1995
18938
Brachat S.,Dietrich F.S.,Voegeli S.,Zhang Z.,Stuart L.,Lerch A.,Gates K.,Gaffney T.D.,Philippsen P.
Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii.
Genome Biol.
4
0-0
2003
18939
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
18940
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
18941
Boumann H.A.,de Kruijff B.,Heck A.J.,de Kroon A.I.
The selective utilization of substrates in vivo by the phosphatidylethanolamine and phosphatidylcholine biosynthetic enzymes Ept1p and Cpt1p in yeast.
FEBS Lett.
569
173-177
2004