Sequence of HTDY_MYCTU
EC Number:4.2.1.119
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(3R)-3-hydroxyacyl-CoA = (2E)-2-enoyl-CoA + H2O
Other sequences found for EC No. 4.2.1.119
General information:
Sequence
0 MAIDPNSIGA VTEPMLFEWT DRDTLLYAIG VGAGTGDLAF TTENSHGIDQ QVLPTYAVIC
60 CPAFGAAAKV GTFNPAALLH GSQGIRLHAP LPAAGKLSVV TEVADIQDKG EGKNAIVVLR
120 GRGCDPESGS LVAETLTTLV LRGQGGFGGA RGERPAAPEF PDRHPDARID MPTREDQALI
180 YRLSGDRNPL HSDPWFATQL AGFPKPILHG LCTYGVAGRA LVAELGGGVA ANITSIAARF
240 TKPVFPGETL STVIWRTEPG RAVFRTEVAG SDGAEARVVL DDGAVEYVAG
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
174085
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
174086
Sacco E.,Legendre V.,Laval F.,Zerbib D.,Montrozier H.,Eynard N.,Guilhot C.,Daffe M.,Quemard A.
Rv3389C from Mycobacterium tuberculosis, a member of the (R)-specific hydratase/dehydratase family.
Biochim. Biophys. Acta
1774
303-311
2007
174087
Gurvitz A.,Hiltunen J.K.,Kastaniotis A.J.
Heterologous expression of mycobacterial proteins in Saccharomyces cerevisiae reveals two physiologically functional 3-hydroxyacyl-thioester dehydratases, HtdX and HtdY, in addition to HadABC and HtdZ.
J. Bacteriol.
191
2683-2690
2009
174088
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
174089
Zhao J.W.,Sun Z.Q.,Zhang X.Y.,Zhang Y.,Liu J.,Ye J.,Chen C.C.,Samten B.,Wang H.H.,Guo X.K.,Zhang S.L.
Mycobacterial 3-hydroxyacyl-l-thioester dehydratase Y derived from Mycobacterium tuberculosis induces COX-2 expression in mouse macrophages through MAPK-NF-kappaB pathway.
Immunol. Lett.
161
125-132
2014
174090
Baugh L.,Phan I.,Begley D.W.,Clifton M.C.,Armour B.,Dranow D.M.,Taylor B.M.,Muruthi M.M.,Abendroth J.,Fairman J.W.,Fox D. III,Dieterich S.H.,Staker B.L.,Gardberg A.S.,Choi R.,Hewitt S.N.,Napuli A.J.,Myers J.,Barrett L.K.,Zhang Y.,Ferrell M.,Mundt E.,Thompkins K.,Tran N.,Lyons-Abbott S.,Abramov A.,Sekar A.,Serbzhinskiy D.,Lorimer D.,Buchko G.W.,Stacy R.,Stewart L.J.,Edwards T.E.,Van Voorhis W.C.,Myler P.J.
Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis
95
142-148
2015
