Sequence of GPDQ_KLEAE
EC Number:3.1.4.46
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
a glycerophosphodiester + H2O = a primary alcohol + sn-glycerol 3-phosphate
Other sequences found for EC No. 3.1.4.46
General information:
Sequence
0 MLLAHISDTH FRSRGEKLYG FIDVNAANAD VVSQLNALRE RPDAVVVSGD IVNCGRPEEY
60 QVARQILGSL NYPLYLIPGN HDDKALFLEY LQPLCPQLGS DANNMRCAVD DFATRLLFID
120 SSRAGTSKGW LTDETISWLE AQLFEGGDKP ATIFMHHPPL PLGNAQMDPI ACENGHRLLA
180 LVERFPSLTR IFCGHNHSLT MTQYRQALIS TLPGTVHQVP YCHEDTRPYY DLSPASCLMH
240 RQVGEQWVSY QHSLAHYAGP WLYDENISCP TEER
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
168173
Yu McLoughlin S.,Jackson C.,Liu J.W.,Ollis D.L.
Growth of Escherichia coli coexpressing phosphotriesterase and glycerophosphodiester phosphodiesterase, using paraoxon as the sole phosphorus source.
Appl. Environ. Microbiol.
70
404-412
2004
168174
Gerlt J.A.,Whitman G.J.
Purification and properties of a phosphohydrolase from Enterobacter aerogenes.
J. Biol. Chem.
250
5053-5058
1975
168175
Jackson C.J.,Carr P.D.,Kim H.K.,Liu J.W.,Ollis D.L.
The purification, crystallization and preliminary diffraction of a glycerophosphodiesterase from Enterobacter aerogenes.
Acta Crystallogr. F
62
659-661
2006
168176
Ghanem E.,Li Y.,Xu C.,Raushel F.M.
Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX.
Biochemistry
46
9032-9040
2007
168177
Mirams R.E.,Smith S.J.,Hadler K.S.,Ollis D.L.,Schenk G.,Gahan L.R.
Cadmium(II) complexes of the glycerophosphodiester-degrading enzyme GpdQ and a biomimetic N,O ligand.
J. Biol. Inorg. Chem.
13
1065-1072
2008
168178
Hadler K.S.,Gahan L.R.,Ollis D.L.,Schenk G.
The bioremediator glycerophosphodiesterase employs a non-processive mechanism for hydrolysis.
J. Inorg. Biochem.
104
211-213
2010
168179
Hadler K.S.,Mitic N.,Yip S.H.,Gahan L.R.,Ollis D.L.,Schenk G.,Larrabee J.A.
Electronic structure analysis of the dinuclear metal center in the bioremediator glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes.
Inorg. Chem.
49
2727-2734
2010
168180
Daumann L.J.,Larrabee J.A.,Ollis D.,Schenk G.,Gahan L.R.
Immobilization of the enzyme GpdQ on magnetite nanoparticles for organophosphate pesticide bioremediation.
J. Inorg. Biochem.
131
1-7
2014
168181
Jackson C.J.,Carr P.D.,Liu J.W.,Watt S.J.,Beck J.L.,Ollis D.L.
The structure and function of a novel glycerophosphodiesterase from Enterobacter aerogenes.
J. Mol. Biol.
367
1047-1062
2007
168182
Jackson C.J.,Hadler K.S.,Carr P.D.,Oakley A.J.,Yip S.,Schenk G.,Ollis D.L.
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference.
Acta Crystallogr. F Struct. Biol. Commun.
64
681-685
2008
168183
Hadler K.S.,Tanifum E.A.,Yip S.H.,Mitic N.,Guddat L.W.,Jackson C.J.,Gahan L.R.,Nguyen K.,Carr P.D.,Ollis D.L.,Hengge A.C.,Larrabee J.A.,Schenk G.
Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes.
J. Am. Chem. Soc.
130
14129-14138
2008
