Sequence of FAXC_OXYSU
EC Number:3.4.21.6
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
selective cleavage of Arg-/-Thr and then Arg-/-Ile bonds in prothrombin to form thrombin
Other sequences found for EC No. 3.4.21.6
General information:
Sequence
0 MAPQLLLCLI LTFLWSLPEA ESNVFLKSKV ANRFLQRTKR ANSLYEEFRS GNIERECIEE
60 RCSKEEAREV FEDDEKTETF WNVYVDGDQC SSNPCHYRGT CKDGIGSYTC TCLSGYEGKN
120 CERVLYKSCR VDNGNCWHFC KPVQNDIQCS CAEGYLLGED GHSCVAGGNF SCGRNIKTRN
180 KREASLPDFV QSQNAILLKK SDNPSPDIRI VNGMDCKLGE CPWQAVLVDE KEDAFCGGTI
240 LSPIYVLTAA HCINQTKMIS VVVGEINISR KNPGRLLSVD KIYVHQKFVP PKKGYEFYEK
300 FDLVSYDYDI AILQMKTPIQ FSENVVPACL PTADFANQVL MKQDFGIVSG FGRIFEKGPQ
360 SKTLKVLKVP YVDRHTCMLS SESPITPTMF CAGYDTLPRD ACQGDSGGPH ITAYRDTHFI
420 TGIVSWGEGC AQTGKYGVYT KVSKFILWIK RIMRQKLPST ESSTGRL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
160767
St Pierre L.,Masci P.P.,Filippovich I.,Sorokina N.,Marsh N.,Miller D.J.,Lavin M.F.
Comparative analysis of prothrombin activators from the venom of Australian elapids.
Mol. Biol. Evol.
22
1853-1864
2005
160768
Walker F.J.,Owen W.G.,Esmon C.T.
Characterization of the prothrombin activator from the venom of Oxyuranus scutellatus scutellatus (taipan venom).
Biochemistry
19
1020-1023
1980
160769
Speijer H.,Govers-Riemslag J.W.P.,Zwaal R.F.A.,Rosing J.
Prothrombin activation by an activator from the venom of Oxyuranus scutellatus (Taipan snake).
J. Biol. Chem.
261
13258-13267
1986
160770
Nakagaki T.,Lin P.,Kisiel W.
Activation of human factor VII by the prothrombin activator from the venom of Oxyuranus scutellatus (Taipan snake).
Thromb. Res.
65
105-116
1992
160771
Manjunatha Kini R.,Morita T.,Rosing J.
Classification and nomenclature of prothrombin activators isolated from snake venoms.
Thromb. Haemost.
86
710-711
2001
