Sequence of DNAG_ECOLI

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
DNA primase DnaG
P0ABS5
Escherichia coli (strain K12)
581
65565
Reaction
ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MAGRIPRVFI NDLLARTDIV DLIDARVKLK KQGKNFHACC PFHNEKTPSF TVNGEKQFYH
 60 CFGCGAHGNA IDFLMNYDKL EFVETVEELA AMHNLEVPFE AGSGPSQIER HQRQTLYQLM
120 DGLNTFYQQS LQQPVATSAR QYLEKRGLSH EVIARFAIGF APPGWDNVLK RFGGNPENRQ
180 SLIDAGMLVT NDQGRSYDRF RERVMFPIRD KRGRVIGFGG RVLGNDTPKY LNSPETDIFH
240 KGRQLYGLYE AQQDNAEPNR LLVVEGYMDV VALAQYGINY AVASLGTSTT ADHIQLLFRA
300 TNNVICCYDG DRAGRDAAWR ALETALPYMT DGRQLRFMFL PDGEDPDTLV RKEGKEAFEA
360 RMEQAMPLSA FLFNSLMPQV DLSTPDGRAR LSTLALPLIS QVPGETLRIY LRQELGNKLG
420 ILDDSQLERL MPKAAESGVS RPVPQLKRTT MRILIGLLVQ NPELATLVPP LENLDENKLP
480 GLGLFRELVN TCLSQPGLTT GQLLEHYRGT NNAATLEKLS MWDDIADKNI AEQTFTDSLN
540 HMFDSLLELR QEELIARERT HGLSNEERLE LWTLNQELAK K
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
527757
Burton Z.F.,Gross C.A.,Watanabe K.K.,Burgess R.R.
The operon that encodes the sigma subunit of RNA polymerase also encodes ribosomal protein S21 and DNA primase in E. coli K12.
Cell
32
335-349
1983
527758
Smiley B.L.,Lupski J.R.,Svec P.S.,McMacken R.,Godson G.N.
Sequences of the Escherichia coli dnaG primase gene and regulation of its expression.
Proc. Natl. Acad. Sci. U.S.A.
79
4550-4554
1982
527759
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
527760
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
527761
Lupski J.R.,Smiley B.L.,Godson G.N.
Regulation of the rpsU-dnaG-rpoD macromolecular synthesis operon and the initiation of DNA replication in Escherichia coli K-12.
Mol. Gen. Genet.
189
48-57
1983
527762
Rowen L.,Kornberg A.
Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chains.
J. Biol. Chem.
253
758-764
1978
527763
Stamford N.P.J.,Lilley P.E.,Dixon N.E.
Enriched sources of Escherichia coli replication proteins. The dnaG primase is a zinc metalloprotein.
Biochim. Biophys. Acta
1132
17-25
1992
527764
Griep M.A.,Lokey E.R.
The role of zinc and the reactivity of cysteines in Escherichia coli primase.
Biochemistry
35
8260-8267
1996
527765
Lu Y.B.,Ratnakar P.V.,Mohanty B.K.,Bastia D.
Direct physical interaction between DnaG primase and DnaB helicase of Escherichia coli is necessary for optimal synthesis of primer RNA.
Proc. Natl. Acad. Sci. U.S.A.
93
12902-12907
1996
527766
VanBogelen R.A.,Abshire K.Z.,Moldover B.,Olson E.R.,Neidhardt F.C.
Escherichia coli proteome analysis using the gene-protein database.
Electrophoresis
18
1243-1251
1997
527767
Mitkova A.V.,Khopde S.M.,Biswas S.B.
Mechanism and stoichiometry of interaction of DnaG primase with DnaB helicase of Escherichia coli in RNA primer synthesis.
J. Biol. Chem.
278
52253-52261
2003
527768
Corn J.E.,Pease P.J.,Hura G.L.,Berger J.M.
Crosstalk between primase subunits can act to regulate primer synthesis in trans.
Mol. Cell
20
391-401
2005
527769
Podobnik M.,McInerney P.,O'Donnell M.,Kuriyan J.
A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases.
J. Mol. Biol.
300
353-362
2000
527770
Keck J.L.,Roche D.D.,Lynch A.S.,Berger J.M.
Structure of the RNA polymerase domain of E. coli primase.
Science
287
2482-2486
2000
527771
Oakley A.J.,Loscha K.V.,Schaeffer P.M.,Liepinsh E.,Pintacuda G.,Wilce M.C.,Otting G.,Dixon N.E.
Crystal and solution structures of the helicase-binding domain of Escherichia coli primase.
J. Biol. Chem.
280
11495-11504
2005
527772
Su X.C.,Schaeffer P.M.,Loscha K.V.,Gan P.H.,Dixon N.E.,Otting G.
Monomeric solution structure of the helicase-binding domain of Escherichia coli DnaG primase.
FEBS J.
273
4997-5009
2006
527773
Corn J.E.,Pelton J.G.,Berger J.M.
Identification of a DNA primase template tracking site redefines the geometry of primer synthesis.
Nat. Struct. Mol. Biol.
15
163-169
2008