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Sequence of PYRF_METTH

EC Number:4.1.1.23

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
orotidine-5'-phosphate decarboxylase
O26232
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
228
24915
Reaction
orotidine 5'-phosphate = UMP + CO2
Other sequences found for EC No. 4.1.1.23

General information:

Sequence
show sequence in fasta format
  0 MRSRRVDVMD VMNRLILAMD LMNRDDALRV TGEVREYIDT VKIGYPLVLS EGMDIIAEFR
 60 KRFGCRIIAD FKVADIPETN EKICRATFKA GADAIIVHGF RGADSVRACL NVAEEMGREV
120 FLLTEMSHPG AEMFIQGAAD EIARMGVDLG VKNYVGPSTR PERLSRLREI IGQDSFLISP
180 GVGAQGGDPG ETLRFADAII VGRSIYLADN PAAAAAGIIE SIKDLLNP
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1236827
Smith D.R.,Doucette-Stamm L.A.,Deloughery C.,Lee H.-M.,Dubois J.,Aldredge T.,Bashirzadeh R.,Blakely D.,Cook R.,Gilbert K.,Harrison D.,Hoang L.,Keagle P.,Lumm W.,Pothier B.,Qiu D.,Spadafora R.,Vicare R.,Wang Y.,Wierzbowski J.,Gibson R.,Jiwani N.,Caruso A.,Bush D.,Safer H.,Patwell D.,Prabhakar S.,McDougall S.,Shimer G.,Goyal A.,Pietrovski S.,Church G.M.,Daniels C.J.,Mao J.-I.,Rice P.,Noelling J.,Reeve J.N.
Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics.
J. Bacteriol.
179
7135-7155
1997
1236828
Wu N.,Christendat D.,Dharamsi A.,Pai E.F.
Purification, crystallization and preliminary X-ray study of orotidine 5'-monophosphate decarboxylase.
Acta Crystallogr. D
56
912-914
2000
1236829
Wu N.,Mo Y.,Gao J.,Pai E.F.
Electrostatic stress in catalysis: structure and mechanism of the enzyme orotidine monophosphate decarboxylase.
Proc. Natl. Acad. Sci. U.S.A.
97
2017-2022
2000
1236830
Wu N.,Gillon W.,Pai E.F.
Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography.
Biochemistry
41
4002-4011
2002
1236831
Wu N.,Pai E.F.
Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase.
J. Biol. Chem.
277
28080-28087
2002
1236832
Fujihashi M.,Bello A.M.,Poduch E.,Wei L.,Annedi S.C.,Pai E.F.,Kotra L.P.
An unprecedented twist to ODCase catalytic activity.
J. Am. Chem. Soc.
127
15048-15050
2005