Sequence of THOP1_RAT
EC Number:3.4.24.15
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Preferential cleavage of bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5-15 residues
Other sequences found for EC No. 3.4.24.15
General information:
Sequence
0 MKPPAACAGD VVDTVSPCST VNHLRWDLSA QQIRALTTQL IEQTKCVYDR VGAQDFEDVS
60 YESTLKALAD VEVTYTVQRN ILDFPQHVSP NKDIRAASTE ADKKLSEFDV EMSMRQDVYQ
120 RVVWLQEKIP KDSLKPEAAR YLERLIKLGR RNGLHLPQDT QEKIKNIKKR LSLLCIDFNK
180 NLNEDTTFLP FTREELGGLP EDFLNSLEKT EDGKLKVTLK YPHYFPLLKK CHVPETRRLL
240 EEAFNCRCKE ENCAILKELV SLRAQKSNLL GFRTHADYVL EMNMAKTSQT VATFLDELAR
300 KLKPLGEQER AVILELKEAE CAKRGLPFDG RIHAWDMRYY MNQVEETRYR VDQNLLKEYF
360 PMQVVTRGLL AIYQELLGLT FTLEEGAAAW HEDVRLYSVR DAASGEEIGK FYLDLYPREG
420 KYGHAACFGL QPGCLRQDGS RQLAIAAMVA NFTKPTPDVP SLLQHDEVET YFHEFGHVMH
480 QLCSQAEFAM FSGTHVERDF VEAPSQMLEN WVWEKEPLMR MSQHYRTGGE APEDLLEKLI
540 KSRQANAGLF NLRQIVLAKV DQVLHTQTDV DPAEEYARLC QEILGVPATP GTNMPATFGH
600 LAGGYDAQYY GYLWSEVYSM DMFHTRFKQE GVLSPKVGMD YRTSILRPGG SEDASTMLKQ
660 FLGRDPKQDA FLLSKGLQVE GCEPPAC
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
108889
Pierotti A.,Dong K.-W.,Glucksman M.J.,Orlowski M.,Roberts J.L.
Molecular cloning and primary structure of rat testes metalloendopeptidase EC 3.4.24.15.
Biochemistry
29
10323-10329
1990
108890
McKie N.,Dando P.M.,Rawlings N.D.,Barrett A.J.
Thimet oligopeptidase: similarity to 'soluble angiotensin II-binding protein' and some corrections to the published amino acid sequence of the rat testis enzyme.
Biochem. J.
295
57-60
1993
108891
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
108893
Rioli V.,Gozzo F.C.,Heimann A.S.,Linardi A.,Krieger J.E.,Shida C.S.,Almeida P.C.,Hyslop S.,Eberlin M.N.,Ferro E.S.
Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme.
J. Biol. Chem.
278
8547-8555
2003
108894
Heimann A.S.,Gomes I.,Dale C.S.,Pagano R.L.,Gupta A.,de Souza L.L.,Luchessi A.D.,Castro L.M.,Giorgi R.,Rioli V.,Ferro E.S.,Devi L.A.
Hemopressin is an inverse agonist of CB1 cannabinoid receptors.
Proc. Natl. Acad. Sci. U.S.A.
104
20588-20593
2007
