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Sequence of SYW_GEOSE

EC Number:6.1.1.2

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tryptophan-tRNA ligase
P00953
Geobacillus stearothermophilus
328
37193
Reaction
ATP + L-tryptophan + tRNATrp = AMP + diphosphate + L-tryptophyl-tRNATrp
Other sequences found for EC No. 6.1.1.2

General information:

Sequence
show sequence in fasta format
  0 MKTIFSGIQP SGVITIGNYI GALRQFVELQ HEYNCYFCIV DQHAITVWQD PHELRQNIRR
 60 LAAKYLAVGI DPTQATLFIQ SEVPAHAQAA WMLQCIVYIG ELERMTQFKE KSAGKEAVSA
120 GLLTYPPLMA ADILLYNTDI VPVGEDQKQH IELTRDLAER FNKRYGELFT IPEARIPKVG
180 ARIMSLVDPT KKMSKSDPNP KAYITLLDDA KTIEKKIKSA VTDSEGTIRY DKEAKPGISN
240 LLNIYSTLSG QSIEELERQY EGKGYGVFKA DLAQVVIETL RPIQERYHHW MESEELDRVL
300 DEGAEKANRV ASEMVRKMEQ AMGLGRRR
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
106216
Barstow D.A.,Sharman A.F.,Atkinson T.,Minton N.P.
Cloning and complete nucleotide sequence of the Bacillus stearothermophilus tryptophanyl tRNA synthetase gene.
Gene
46
37-45
1986
106217
Winter G.P.,Hartley B.S.
The amino acid sequence of tryptophanyl tRNA synthetase from Bacillus stearothermophilus.
FEBS Lett.
80
340-342
1977
106218
Doublie S.,Bricogne G.,Gilmore C.,Carter C.W. Jr.
Tryptophanyl-tRNA synthetase crystal structure reveals an unexpected homology to tyrosyl-tRNA synthetase.
Structure
3
17-31
1995
106219
Ilyin V.A.,Temple B.,Hu M.,Li G.-P.,Yin Y.,Vachette P.,Carter C.W. Jr.
2.9-A crystal structure of ligand-free tryptophanyl-tRNA synthetase: domain movements fragment the adenine nucleotide binding site.
Protein Sci.
9
218-231
2000
106220
Williams T.L.,Yin Y.W.,Carter C.W. Jr.
Selective inhibition of bacterial tryptophanyl-tRNA synthetases by Indolmycin is mechanism-based.
J. Biol. Chem.
291
255-265
2016