Sequence of REBO_NOCAE

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
7-chloro-L-tryptophan oxidase
Q8KHS0
Lechevalieria aerocolonigenes
473
51897
Reaction
7-chloro-L-tryptophan + O2 = 2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MSRGHKKITV LGAGVAGLVA AHELEELGHE VEVLEGSDRL GGRVHTHRFG EGGSVPFVEL
 60 GAMRIPTKHR HTIDYIGKLG LTPKLKEFKT LFSDDGAYHT TSAGFVRVRD AAKVLVDEFR
120 LLMSGRDLRE ETILFGAWLT AVGDAIAPAD FRAALRTDFT ADLLEVVDRI DLDPFLVGAA
180 RDQFDLHAFF AAHPEVRTSC TGKLNRFVDD ILDETSPRLL RLEGGMDQLV DALVERIRGD
240 IRTGHEVSAI DVREDHVAVT VHNGHGVNTL RSDHVLCTIP FSVLRNLRLT GLSTDKLEII
300 HDVKYWSATK VAFRCREPFW ERDGINGGAS FGGGRIRQTY YPPVEGDPTR GAVLLASYTM
360 GDDADVLGGM PEAQRHEVVL DEVGRMHPEL HEPGMVVEAV SRAWGEDRWS NGAGVTRWGK
420 DVAACEEERD RAARPEGRLY FAGEHCSSTT AWIDGAVESA LAAVRAIEAG DGR
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1059065
Sanchez C.,Butovich I.A.,Brana A.F.,Rohr J.,Mendez C.,Salas J.A.
The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives.
Chem. Biol.
9
519-531
2002
1059066
Onaka H.,Taniguchi S.,Igarashi Y.,Furumai T.
Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.
J. Antibiot.
55
1063-1071
2002
1059068
Onaka H.,Taniguchi S.,Igarashi Y.,Furumai T.
Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243.
Biosci. Biotechnol. Biochem.
67
127-138
2003
1059069
Onaka H.,Taniguchi S.,Ikeda H.,Igarashi Y.,Furumai T.
pTOYAMAcos, pTYM18, and pTYM19, actinomycete-Escherichia coli integrating vectors for heterologous gene expression.
J. Antibiot.
56
950-956
2003
1059070
Nishizawa T.,Aldrich C.C.,Sherman D.H.
Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243.
J. Bacteriol.
187
2084-2092
2005
1059073
Howard-Jones A.R.,Walsh C.T.
Enzymatic generation of the chromopyrrolic acid scaffold of rebeccamycin by the tandem action of RebO and RebD.
Biochemistry
44
15652-15663
2005
1059074
Spolitak T.,Ballou D.P.
Evidence for catalytic intermediates involved in generating the chromopyrrolic acid scaffold of rebeccamycin by RebO and RebD.
Arch. Biochem. Biophys.
573
111-119
2015