Sequence of RPOBC_HELPY
EC Number:2.7.7.6
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
DNA-directed RNA polymerase
O25806
Helicobacter pylori (strain ATCC 700392 / 26695)
2890
323575
Reaction
nucleoside triphosphate + RNAn = diphosphate + RNAn+1
Other sequences found for EC No. 2.7.7.6
General information:
Sequence
0 MSKKIPLKNR LRADFTKTPT DLEVPNLLLL QRDSYDSFLY SKEGKESGIE KVFKSIFPIQ
60 DEHNRITLEY AGCEFGKSKY TVREAMERGI TYSIPLKIKV RLILWEKDTK SGEKNGIKDI
120 KEQSIFIREI PLMTERTSFI INGVERVVVN QLHRSPGVIF KEEESSTSLN KLIYTGQIIP
180 DRGSWLYFEY DSKDVLYARI NKRRKVPVTI LFRAMDYQKQ DIIKMFYPLV KVRYENDKYL
240 IPFASLDANQ RMEFDLKDPQ GKVILLAGKK LTSRKIKELK ENHLEWVEYP MDILLNRHLA
300 EPVMVGKEVL LDMLTQLDKN KLEKIHDLGV QEFVIINDLA LGHDASIIQS FSADSESLKL
360 LKQTEKIDDE NALAAIRIHK VMKPGDPVTT EVAKQFVKKL FFDPERYDLT MVGRMKMNHK
420 LGLHVPDYIT TLTHEDIITT VKYLMKIKNN QGKIDDRDHL GNRRIRAVGE LLANELHSGL
480 VKMQKTIKDK LTTMSGAFDS LMPHDLVNSK MITSTIMEFF MGGQLSQFMD QTNPLSEVTH
540 KRRLSALGEG GLVKDRVGFE ARDVHPTHYG RICPIETPEG QNIGLINTLS TFTRVNDLGF
600 IEAPYKKVVD GKVVGETIYL TAIQEDSHII APASTPIDEE GNILGDLIET RVEGEIVLNE
660 KSKVTLMDLS SSMLVGVAAS LIPFLEHDDA NRALMGTNMQ RQAVPLLRSD APIVGTGIEK
720 IIARDSWGAI KANRAGVVEK IDSKNIYILG ESKEEAYIDA YSLQKNLRTN QNTSFNQVPI
780 VKVGDKVGAG QIIADGPSMD RGELALGKNV RVAFMPWNGY NFEDAIVVSE CITKDDIFTS
840 THIYEKEVDA RELKHGVEEF TADIPDVKEE ALAHLDESGI VKVGTYVSAG MILVGKTSPK
900 GEIKSTPEER LLRAIFGDKA GHVVNKSLYC PPSLEGTVID VKVFTKKGYE KDARVLSAYE
960 EEKAKLDMEH FDRLTMLNRE ELLRVSSLLS QAILEEPFSH NGKDYKEGDQ IPKEEIASIN
1020 RFTLASLVKK YSKEVQNHYE ITKNNFLEQK KVLGEEHEEK LSILEKDDIL PNGVIKKVKL
1080 YIATKRKLKV GDKMAGRHGN KGIVSNIVPV ADMPYTADGE PVDIVLNPLG VPSRMNIGQI
1140 LEMHLGLVGK EFGKQIARML EDKTKDFAKE LRAKMLEIAN AINEKDPLTI HALENCSDEE
1200 LLEYAKDWSK GVKMAIPVFE GISQEKFYKL FELAKIAMDG KMDLYDGRTG EKMRERVNVG
1260 YMYMIKLHHL VDEKVHARST GPYSLVTHQP VGGKALFGGQ RFGEMEVWAL EAYGAAHTLK
1320 EMLTIKSDDI RGRENAYRAI AKGEQVGESE IPETFYVLTK ELQSLALDIN IFGDDVDEDG
1380 APKPIVIKED DRPKDFSSFQ LTLASPEKIH SWSYGEVKKP ETINYRTLKP ERDGLFCMKI
1440 FGPTKDYECL CGKYKKPRFK DIGTCEKCGV AITHSKVRRF RMGHIELATP VAHIWYVNSL
1500 PSRIGTLLGV KMKDLERVLY YEAYIVKEPG EAAYDNEGTK LVMKYDILNE EQYQNISRRY
1560 EDRGFVAQMG GEAIKDLLEE IDLITLLQSL KEEVKDTNSD AKKKKLIKRL KVVESFLNSG
1620 NRPEWMMLTV LPVLPPDLRP LVALDGGKFA VSDVNELYRR VINRNQRLKR LMELGAPEII
1680 VRNEKRMLQE AVDVLFDNGR STNAVKGANK RPLKSLSEII KGKQGRFRQN LLGKRVDFSG
1740 RSVIVVGPNL KMDECGLPKN MALELFKPHL LSKLEERGYA TTLKQAKRMI EQKSNEVWEC
1800 LQEITEGYPV LLNRAPTLHK QSIQAFHPKL IDGKAIQLHP LVCSAFNADF DGDQMAVHVP
1860 LSQEAIAECK VLMLSSMNIL LPASGKAVAI PSQDMVLGLY YLSLEKSGVK GEHKLFSSVN
1920 EIITAIDTKE LDIHAKIRVL DQGNIIATSA GRMIIKSILP DFIPTDLWNR PMKKKDIGVL
1980 VDYVHKVGGI GITATFLDNL KTLGFRYATK AGISISMEDI ITPKDKQKMV EKAKVEVKKI
2040 QQQYDQGLLT DQERYNKIID TWTEVNDKMS KEMMTAIAQD KEGFNSIYMM ADSGARGSAA
2100 QIRQLSAMRG LMTKPDGSII ETPIISNFKE GLNVLEYFNS THGARKGLAD TALKTANAGY
2160 LTRKLIDVSQ NVKVVSDDCG THEGIEITDI AVGSELIEPL EERIFGRVLL EDVIDPITNE
2220 ILLYADTLID EEGAKKVVEA GIKSITIRTP VTCKAPKGVC AKCYGLNLGE GKMSYPGEAV
2280 GVVAAQSIGE PGTQLTLRTF HVGGTASRSQ DEREIVASKE GFVRFYNLRT YTNKEGKNII
2340 ANRRNASILV VEPKIKAPFD GELRIETVYE EVVVSVKNGD QEAKFVLRRS DIVKPSELAG
2400 VGGKIEGKVY LPYASGHKVH KGGSIADIIQ EGWNVPNRIP YASELLVKDN DPIAQDVYAK
2460 EKGVIKYYVL EANHLERTHG IKKGDMVSEK GLFAVIADDN GREAARHYIA RGSEILIDDN
2520 SEVSTNSVIS KPTTNTFKTI ATWDPYNTPI IADFKGKVGF VDVIAGVTVA EKEDENTGIT
2580 SLVVNDYIPS GYKPSLFLEG ANGEEMRYFL EPKTSIAISD GSSVEQAEVL AKIPKATVKS
2640 RDITGGLPRV SELFEARKPK PKDVAILSEV DGIVSFGKPI RNKEHIIVTS KDGRSMDYFV
2700 DKGKQILVHA DEFVHAGEAM TDGVISSHDI LRISGEKELY KYIVSEVQQV YRRQGVSIAD
2760 KHIEIIVSQM LRQVRILDSG DSKFIEGDLV SKKLFKEENA RVIALKGEPA IAEPVLLGIT
2820 RAAIGSDSII SAASFQETTK VLTEASIAMK KDFLEDLKEN VVLGRMIPVG TGMYKNKKIV
2880 LRALEDNSKF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
91802
Tomb J.-F.,White O.,Kerlavage A.R.,Clayton R.A.,Sutton G.G.,Fleischmann R.D.,Ketchum K.A.,Klenk H.-P.,Gill S.R.,Dougherty B.A.,Nelson K.E.,Quackenbush J.,Zhou L.,Kirkness E.F.,Peterson S.N.,Loftus B.J.,Richardson D.L.,Dodson R.J.,Khalak H.G.,Glodek A.,McKenney K.,FitzGerald L.M.,Lee N.,Adams M.D.,Hickey E.K.,Berg D.E.,Gocayne J.D.,Utterback T.R.,Peterson J.D.,Kelley J.M.,Cotton M.D.,Weidman J.F.,Fujii C.,Bowman C.,Watthey L.,Wallin E.,Hayes W.S.,Borodovsky M.,Karp P.D.,Smith H.O.,Fraser C.M.,Venter J.C.
The complete genome sequence of the gastric pathogen Helicobacter pylori.
Nature
388
539-547
1997
91803
Zakharova N.,Hoffman P.S.,Berg D.E.,Severinov K.
The largest subunits of RNA polymerase from gastric helicobacters are tethered.
J. Biol. Chem.
273
19371-19374
1998
91804
Raudonikiene A.,Zakharova N.,Su W.W.,Jeong J.-Y.,Bryden L.,Hoffman P.S.,Berg D.E.,Severinov K.
Helicobacter pylori with separate beta- and beta'-subunits of RNA polymerase is viable and can colonize conventional mice.
Mol. Microbiol.
32
131-138
1999
