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Sequence of REP68_AAV2S

EC Number:3.6.4.12

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
DNA helicase
P03132
Adeno-associated virus 2 (isolate Srivastava/1982)
536
60754
Reaction
Other sequences found for EC No. 3.6.4.12

General information:

Sequence
show sequence in fasta format
  0 MPGFYEIVIK VPSDLDGHLP GISDSFVNWV AEKEWELPPD SDMDLNLIEQ APLTVAEKLQ
 60 RDFLTEWRRV SKAPEALFFV QFEKGESYFH MHVLVETTGV KSMVLGRFLS QIREKLIQRI
120 YRGIEPTLPN WFAVTKTRNG AGGGNKVVDE CYIPNYLLPK TQPELQWAWT NMEQYLSACL
180 NLTERKRLVA QHLTHVSQTQ EQNKENQNPN SDAPVIRSKT SARYMELVGW LVDKGITSEK
240 QWIQEDQASY ISFNAASNSR SQIKAALDNA GKIMSLTKTA PDYLVGQQPV EDISSNRIYK
300 ILELNGYDPQ YAASVFLGWA TKKFGKRNTI WLFGPATTGK TNIAEAIAHT VPFYGCVNWT
360 NENFPFNDCV DKMVIWWEEG KMTAKVVESA KAILGGSKVR VDQKCKSSAQ IDPTPVIVTS
420 NTNMCAVIDG NSTTFEHQQP LQDRMFKFEL TRRLDHDFGK VTKQEVKDFF RWAKDHVVEV
480 EHEFYVKKGG AKKRPAPSDA DISEPKRVRE SVAQPSTSDA EASINYADRL ARGHSL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
981232
Srivastava A.,Lusby E.W.,Berns K.I.
Nucleotide sequence and organization of the adeno-associated virus 2 genome.
J. Virol.
45
555-564
1983
981233
Ruffing M.,Heid H.,Kleinschmidt J.A.
Mutations in the carboxy terminus of adeno-associated virus 2 capsid proteins affect viral infectivity: lack of an RGD integrin-binding motif.
J. Gen. Virol.
75
3385-3392
1994
981235
Hunter L.A.,Samulski R.J.
Colocalization of adeno-associated virus Rep and capsid proteins in the nuclei of infected cells.
J. Virol.
66
317-324
1992
981236
Zhou X.,Zolotukhin I.,Im D.S.,Muzyczka N.
Biochemical characterization of adeno-associated virus rep68 DNA helicase and ATPase activities.
J. Virol.
73
1580-1590
1999
981237
Weger S.,Wendland M.,Kleinschmidt J.A.,Heilbronn R.
The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4.
J. Virol.
73
260-269
1999
981238
Weger S.,Hammer E.,Heilbronn R.
Topors, a p53 and topoisomerase I binding protein, interacts with the adeno-associated virus (AAV-2) Rep78/68 proteins and enhances AAV-2 gene expression.
J. Gen. Virol.
83
511-516
2002
981239
Weger S.,Hammer E.,Goetz A.,Heilbronn R.
Identification of a cytoplasmic interaction partner of the large regulatory proteins Rep78/Rep68 of adeno-associated virus type 2 (AAV-2).
Virology
362
192-206
2007
981240
James J.A.,Escalante C.R.,Yoon-Robarts M.,Edwards T.A.,Linden R.M.,Aggarwal A.K.
Crystal structure of the SF3 helicase from adeno-associated virus type 2.
Structure
11
1025-1035
2003
981241
James J.A.,Aggarwal A.K.,Linden R.M.,Escalante C.R.
Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases.
Proc. Natl. Acad. Sci. U.S.A.
101
12455-12460
2004