Sequence of AASS_HUMAN

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
saccharopine dehydrogenase (NAD+, L-glutamate-forming)
Q9UDR5
Homo sapiens
926
102132
Reaction
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-glutamate + (S)-2-amino-6-oxohexanoate + NADH + H+
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MLQVHRTGLG RLGVSLSKGL HHKAVLAVRR EDVNAWERRA PLAPKHIKGI TNLGYKVLIQ
 60 PSNRRAIHDK DYVKAGGILQ EDISEACLIL GVKRPPEEKL MSRKTYAFFS HTIKAQEANM
120 GLLDEILKQE IRLIDYEKMV DHRGVRVVAF GQWAGVAGMI NILHGMGLRL LALGHHTPFM
180 HIGMAHNYRN SSQAVQAVRD AGYEISLGLM PKSIGPLTFV FTGTGNVSKG AQAIFNELPC
240 EYVEPHELKE VSQTGDLRKV YGTVLSRHHH LVRKTDAVYD PAEYDKHPER YISRFNTDIA
300 PYTTCLINGI YWEQNTPRLL TRQDAQSLLA PGKFSPAGVE GCPALPHKLV AICDISADTG
360 GSIEFMTECT TIEHPFCMYD ADQHIIHDSV EGSGILMCSI DNLPAQLPIE ATECFGDMLY
420 PYVEEMILSD ATQPLESQNF SPVVRDAVIT SNGTLPDKYK YIQTLRESRE RAQSLSMGTR
480 RKVLVLGSGY ISEPVLEYLS RDGNIEITVG SDMKNQIEQL GKKYNINPVS MDICKQEEKL
540 GFLVAKQDLV ISLLPYVLHP LVAKACITNK VNMVTASYIT PALKELEKSV EDAGITIIGE
600 LGLDPGLDHM LAMETIDKAK EVGATIESYI SYCGGLPAPE HSNNPLRYKF SWSPVGVLMN
660 VMQSATYLLD GKVVNVAGGI SFLDAVTSMD FFPGLNLEGY PNRDSTKYAE IYGISSAHTL
720 LRGTLRYKGY MKALNGFVKL GLINREALPA FRPEANPLTW KQLLCDLVGI SPSSEHDVLK
780 EAVLKKLGGD NTQLEAAEWL GLLGDEQVPQ AESILDALSK HLVMKLSYGP EEKDMIVMRD
840 SFGIRHPSGH LEHKTIDLVA YGDINGFSAM AKTVGLPTAM AAKMLLDGEI GAKGLMGPFS
900 KEIYGPILER IKAEGIIYTT QSTIKP
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
979049
Sacksteder K.A.,Biery B.J.,Morrell J.C.,Goodman B.K.,Geisbrecht B.V.,Cox R.P.,Gould S.J.,Geraghty M.T.
Identification of the alpha-aminoadipic semialdehyde synthase gene, which is defective in familial hyperlysinemia.
Am. J. Hum. Genet.
66
1736-1743
2000
979051
Hillier L.W.,Fulton R.S.,Fulton L.A.,Graves T.A.,Pepin K.H.,Wagner-McPherson C.,Layman D.,Maas J.,Jaeger S.,Walker R.,Wylie K.,Sekhon M.,Becker M.C.,O'Laughlin M.D.,Schaller M.E.,Fewell G.A.,Delehaunty K.D.,Miner T.L.,Nash W.E.,Cordes M.,Du H.,Sun H.,Edwards J.,Bradshaw-Cordum H.,Ali J.,Andrews S.,Isak A.,Vanbrunt A.,Nguyen C.,Du F.,Lamar B.,Courtney L.,Kalicki J.,Ozersky P.,Bielicki L.,Scott K.,Holmes A.,Harkins R.,Harris A.,Strong C.M.,Hou S.,Tomlinson C.,Dauphin-Kohlberg S.,Kozlowicz-Reilly A.,Leonard S.,Rohlfing T.,Rock S.M.,Tin-Wollam A.-M.,Abbott A.,Minx P.,Maupin R.,Strowmatt C.,Latreille P.,Miller N.,Johnson D.,Murray J.,Woessner J.P.,Wendl M.C.,Yang S.-P.,Schultz B.R.,Wallis J.W.,Spieth J.,Bieri T.A.,Nelson J.O.,Berkowicz N.,Wohldmann P.E.,Cook L.L.,Hickenbotham M.T.,Eldred J.,Williams D.,Bedell J.A.,Mardis E.R.,Clifton S.W.,Chissoe S.L.,Marra M.A.,Raymond C.,Haugen E.,Gillett W.,Zhou Y.,James R.,Phelps K.,Iadanoto S.,Bubb K.,Simms E.,Levy R.,Clendenning J.,Kaul R.,Kent W.J.,Furey T.S.,Baertsch R.A.,Brent M.R.,Keibler E.,Flicek P.,Bork P.,Suyama M.,Bailey J.A.,Portnoy M.E.,Torrents D.,Chinwalla A.T.,Gish W.R.,Eddy S.R.,McPherson J.D.,Olson M.V.,Eichler E.E.,Green E.D.,Waterston R.H.,Wilson R.K.
The DNA sequence of human chromosome 7.
Nature
424
157-164
2003
979052
Dancis J.,Hutzler J.,Cox R.P.
Familial hyperlysinemia: enzyme studies, diagnostic methods, comments on terminology.
Am. J. Hum. Genet.
31
290-299
1979
979053
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
979054
Houten S.M.,Denis S.,Te Brinke H.,Jongejan A.,van Kampen A.H.,Bradley E.J.,Baas F.,Hennekam R.C.,Millington D.S.,Young S.P.,Frazier D.M.,Gucsavas-Calikoglu M.,Wanders R.J.
Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia.
Hum. Mol. Genet.
23
5009-5016
2014
979055
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014