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Sequence of FUMH_YEAST

EC Number:4.2.1.2

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
fumarate hydratase
P08417
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
488
53152
Reaction
(S)-malate = fumarate + H2O
Other sequences found for EC No. 4.2.1.2

General information:

Sequence
show sequence in fasta format
  0 MLRFTNCSCK TFVKSSYKLN IRRMNSSFRT ETDAFGEIHV PADKYWGAQT QRSFQNFKIG
 60 GARERMPLPL VHAFGVLKKS AAIVNESLGG LDPKISKAIQ QAADEVASGK LDDHFPLVVF
120 QTGSGTQSNM NANEVISNRA IEILGGKIGS KQVHPNNHCN QSQSSNDTFP TVMHIAASLQ
180 IQNELIPELT NLKNALEAKS KEFDHIVKIG RTHLQDATPL TLGQEFSGYV QQVENGIQRV
240 AHSLKTLSFL AQGGTAVGTG LNTKPGFDVK IAEQISKETG LKFQTAPNKF EALAAHDAIV
300 ECSGALNTLA CSLFKIAQDI RYLGSGPRCG YHELMLPENE PGSSIMPGKV NPTQNEALTQ
360 VCVQVMGNNA AITFAGSQGQ FELNVFKPVM IANLLNSIRL ITDAAYSFRV HCVEGIKANE
420 PRIHELLTKS LMLVTALNPK IGYDAASKVA KNAHKKGITL KESALELGVL TEKEFDEWVV
480 PEHMLGPK
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
929856
Wu M.,Tzagoloff A.
Mitochondrial and cytoplasmic fumarases in Saccharomyces cerevisiae are encoded by a single nuclear gene FUM1.
J. Biol. Chem.
262
12275-12282
1987
929857
Bussey H.,Storms R.K.,Ahmed A.,Albermann K.,Allen E.,Ansorge W.,Araujo R.,Aparicio A.,Barrell B.G.,Badcock K.,Benes V.,Botstein D.,Bowman S.,Brueckner M.,Carpenter J.,Cherry J.M.,Chung E.,Churcher C.M.,Coster F.,Davis K.,Davis R.W.,Dietrich F.S.,Delius H.,DiPaolo T.,Dubois E.,Duesterhoeft A.,Duncan M.,Floeth M.,Fortin N.,Friesen J.D.,Fritz C.,Goffeau A.,Hall J.,Hebling U.,Heumann K.,Hilbert H.,Hillier L.W.,Hunicke-Smith S.,Hyman R.W.,Johnston M.,Kalman S.,Kleine K.,Komp C.,Kurdi O.,Lashkari D.,Lew H.,Lin A.,Lin D.,Louis E.J.,Marathe R.,Messenguy F.,Mewes H.-W.,Mirtipati S.,Moestl D.,Mueller-Auer S.,Namath A.,Nentwich U.,Oefner P.,Pearson D.,Petel F.X.,Pohl T.M.,Purnelle B.,Rajandream M.A.,Rechmann S.,Rieger M.,Riles L.,Roberts D.,Schaefer M.,Scharfe M.,Scherens B.,Schramm S.,Schroeder M.,Sdicu A.-M.,Tettelin H.,Urrestarazu L.A.,Ushinsky S.,Vierendeels F.,Vissers S.,Voss H.,Walsh S.V.,Wambutt R.,Wang Y.,Wedler E.,Wedler H.,Winnett E.,Zhong W.-W.,Zollner A.,Vo D.H.,Hani J.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Nature
387
103-105
1997
929858
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
929859
Sass E.,Blachinsky E.,Karniely S.,Pines O.
Mitochondrial and cytosolic isoforms of yeast fumarase are derivatives of a single translation product and have identical amino termini.
J. Biol. Chem.
276
46111-46117
2001
929860
Grandier-Vazeille X.,Bathany K.,Chaignepain S.,Camougrand N.,Manon S.,Schmitter J.-M.
Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.
Biochemistry
40
9758-9769
2001
929861
Kaclikova E.,Lachowicz T.M.,Gbelska Y.,Subik J.
Fumaric acid overproduction in yeast mutants deficient in fumarase.
FEMS Microbiol. Lett.
70
101-106
1992
929862
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
929863
Reinders J.,Wagner K.,Zahedi R.P.,Stojanovski D.,Eyrich B.,van der Laan M.,Rehling P.,Sickmann A.,Pfanner N.,Meisinger C.
Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.
Mol. Cell. Proteomics
6
1896-1906
2007
929864
Yogev O.,Yogev O.,Singer E.,Shaulian E.,Goldberg M.,Fox T.D.,Pines O.
Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.
PLoS Biol.
8
0-0
2010
929865
Weaver T.,Lees M.,Zaitsev V.,Zaitseva I.,Duke E.,Lindley P.,McSweeny S.,Svensson A.,Keruchenko J.,Keruchenko I.,Gladilin K.,Banaszak L.
Crystal structures of native and recombinant yeast fumarase.
J. Mol. Biol.
280
431-442
1998