Sequence of CDK2_MOUSE
EC Number:2.7.11.22
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.22
General information:
Sequence
0 MENFQKVEKI GEGTYGVVYK AKNKLTGEVV ALKKIRLDTE TEGVPSTAIR EISLLKELNH
60 PNIVKLLDVI HTENKLYLVF EFLHQDLKKF MDASALTGIP LPLIKSYLFQ LLQGLAFCHS
120 HRVLHRDLKP QNLLINAEGS IKLADFGLAR AFGVPVRTYT HEVVTLWYRA PEILLGCKYY
180 STAVDIWSLG CIFAEMHLVC TQHHAKCCGE HRRNGRHSLC PLCSYLEVAA SQGGGMTAVS
240 APHPVTRRAL FPGDSEIDQL FRIFRTLGTP DEVVWPGVTS MPDYKPSFPK WARQDFSKVV
300 PPLDEDGRSL LSQMLHYDPN KRISAKAALA HPFFQDVTKP VPHLRL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
908730
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
908731
Wu C.-L.,Kirley S.D.,Xiao H.,Chuang Y.,Chung D.C.,Zukerberg L.R.
Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers.
Cancer Res.
61
7325-7332
2001
908732
Yamochi T.,Semba K.,Tsuji K.,Mizumoto K.,Sato H.,Matsuura Y.,Nishimoto I.,Matsuoka M.
ik3-1/Cables is a substrate for cyclin-dependent kinase 3 (cdk 3).
Eur. J. Biochem.
268
6076-6082
2001
908733
Berthet C.,Aleem E.,Coppola V.,Tessarollo L.,Kaldis P.
Cdk2 knockout mice are viable.
Curr. Biol.
13
1775-1785
2003
908734
Ortega S.,Prieto I.,Odajima J.,Martin A.,Dubus P.,Sotillo R.,Barbero J.L.,Malumbres M.,Barbacid M.
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.
Nat. Genet.
35
25-31
2003
908735
Wang G.L.,Iakova P.,Wilde M.,Awad S.,Timchenko N.A.
Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity.
Genes Dev.
18
912-925
2004
908736
Satyanarayana A.,Hilton M.B.,Kaldis P.
p21 Inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint.
Mol. Biol. Cell
19
65-77
2008
908737
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
908738
Morawski P.A.,Mehra P.,Chen C.,Bhatti T.,Wells A.D.
Foxp3 protein stability is regulated by cyclin-dependent kinase 2.
J. Biol. Chem.
288
24494-24502
2013
