Sequence of ATP4A_PIG

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
H+/K+-exchanging ATPase
P19156
Sus scrofa
1034
114287
Reaction
ATP + H2O + H+[side 1] + K+[side 2] = ADP + phosphate + H+[side 2] + K+[side 1]
Sequences with same EC No.
Sequence
show sequence in fasta format
   0 MGKAENYELY QVELGPGPSG DMAAKMSKKK AGRGGGKRKE KLENMKKEME INDHQLSVAE
  60 LEQKYQTSAT KGLSASLAAE LLLRDGPNAL RPPRGTPEYV KFARQLAGGL QCLMWVAAAI
 120 CLIAFAIQAS EGDLTTDDNL YLALALIAVV VVTGCFGYYQ EFKSTNIIAS FKNLVPQQAT
 180 VIRDGDKFQI NADQLVVGDL VEMKGGDRVP ADIRILQAQG RKVDNSSLTG ESEPQTRSPE
 240 CTHESPLETR NIAFFSTMCL EGTAQGLVVN TGDRTIIGRI ASLASGVENE KTPIAIEIEH
 300 FVDIIAGLAI LFGATFFIVA MCIGYTFLRA MVFFMAIVVA YVPEGLLATV TVCLSLTAKR
 360 LASKNCVVKN LEAVETLGST SVICSDKTGT LTQNRMTVSH LWFDNHIHSA DTTEDQSGQT
 420 FDQSSETWRA LCRVLTLCNR AAFKSGQDAV PVPKRIVIGD ASETALLKFS ELTLGNAMGY
 480 RERFPKVCEI PFNSTNKFQL SIHTLEDPRD PRHVLVMKGA PERVLERCSS ILIKGQELPL
 540 DEQWREAFQT AYLSLGGLGE RVLGFCQLYL SEKDYPPGYA FDVEAMNFPT SGLSFAGLVS
 600 MIDPPRATVP DAVLKCRTAG IRVIMVTGDH PITAKAIAAS VGIISEGSET VEDIAARLRV
 660 PVDQVNRKDA RACVINGMQL KDMDPSELVE ALRTHPEMVF ARTSPQQKLV IVESCQRLGA
 720 IVAVTGDGVN DSPALKKADI GVAMGIAGSD AAKNAADMIL LDDNFASIVT GVEQGRLIFD
 780 NLKKSIAYTL TKNIPELTPY LIYITVSVPL PLGCITILFI ELCTDIFPSV SLAYEKAESD
 840 IMHLRPRNPK RDRLVNEPLA AYSYFQIGAI QSFAGFTDYF TAMAQEGWFP LLCVGLRPQW
 900 ENHHLQDLQD SYGQEWTFGQ RLYQQYTCYT VFFISIEMCQ IADVLIRKTR RLSAFQQGFF
 960 RNRILVIAIV FQVCIGCFLC YCPGMPNIFN FMPIRFQWWL VPMPFGLLIF VYDEIRKLGV
1020 RCCPGSWWDQ ELYY
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
887334
Maeda M.,Ishizaki J.,Futai M.
cDNA cloning and sequence determination of pig gastric (H+ + K+)-ATPase.
Biochem. Biophys. Res. Commun.
157
203-209
1988
887335
Lane L.K.,Kirley T.L.,Ball W.J. Jr.
Structural studies on H+,K+-ATPase: determination of the NH2-terminal amino acid sequence and immunological cross-reactivity with Na+,K+-ATPase.
Biochem. Biophys. Res. Commun.
138
185-192
1986
887336
Togawa K.,Kaya S.,Shimada A.,Imagawa T.,Maardh S.,Corbin J.,Kikkawa U.,Taniguchi K.
Ser-27, Tyr-10 and Tyr-7 in the alpha-chain of pig stomach H+,K(+)-ATPase as Ca(2+)-dependent phosphorylatable sites by intrinsic and extrinsic protein kinases.
Biochem. Biophys. Res. Commun.
227
810-815
1996
887337
Van Uem T.J.,Swarts H.G.,De Pont J.J.
Determination of the epitope for the inhibitory monoclonal antibody 5-B6 on the catalytic subunit of gastric Mg(2+)-dependent H(+)-transporting and K(+)-stimulated ATPase.
Biochem. J.
280
243-248
1991
887338
Togawa K.,Ishiguro T.,Kaya S.,Shimada A.,Imagawa T.,Taniguchi K.
Reversible phosphorylation of both Tyr7 and Tyr10 in the alpha-chain of pig stomach H+,K(+)-ATPase by a membrane-bound kinase and a phosphatase.
J. Biol. Chem.
270
15475-15478
1995
887339
Abe K.,Tani K.,Fujiyoshi Y.
Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant.
Nat. Commun.
2
155-155
2011