Sequence of VM3BP_BOTJA
EC Number:3.4.24.49
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Cleavage of His5-/-Leu, His10-/-Leu, Ala14-/-Leu, Tyr16-/-Leu and Phe24-/-Phe in insulin B chain
Other sequences found for EC No. 3.4.24.49
General information:
Sequence
0 MIEVLLVTIC LAAFPYQGSS IILESGNVND YEVVYPRKVT ALPKGAVQPK YEDAMQYEFK
60 VNGEPVVLHL EKNKGLFSKD YSETHYSPDG REITTYPAVE DHCYYHGRIE NDADSTASIS
120 ACNGLKGHFK LQRETYFIEP LKLSNSEAHA VFKYENVEKE DEAPKMCGVT QNWKSYEPIK
180 KASQLVVTAE QQKYNPFRYV ELFIVVDQGM VTKNNGDLDK IKARMYELAN IVNEILRYLY
240 MHAALVGLEI WSNGDKITVK PDVDYTLNSF AEWRKTDLLT RKKHDNAQLL TAIDFNGPTI
300 GYAYIGSMCH PKRSVAIVED YSPINLVVAV IMAHEMGHNL GIHHDTDFCS CGDYPCIMGP
360 TISNEPSKFF SNCSYIQCWD FIMKENPQCI LNEPLGTDIV SPPVCGNELL EVGEECDCGT
420 PENCQNECCD AATCKLKSGS QCGHGDCCEQ CKFSKSGTEC RASMSECDPA EHCTGQSSEC
480 PADVFHKNGQ PCLDNYGYCY NGNCPIMYHQ CYALFGADVY EAEDSCFKDN QKGNYYGYCR
540 KENGKKIPCA PEDVKCGRLY CKDNSPGQNN PCKMFYSNDD EHKGMVLPGT KCADGKVCSN
600 GHCVDVATAY
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
882876
Assakura M.T.,Silva C.A.,Mentele R.,Camargo A.C.M.,Serrano S.M.T.
Molecular cloning and expression of structural domains of bothropasin, a P-III metalloproteinase from the venom of Bothrops jararaca.
Toxicon
41
217-227
2003
882877
Mandelbaum F.R.,Reichel A.P.,Assakura M.T.
Isolation and characterization of a proteolytic enzyme from the venom of the snake Bothrops jararaca (Jararaca).
Toxicon
20
955-972
1982
882878
Muniz J.R.C.,Ambrosio A.L.B.,Selistre-de-Araujo H.S.,Cominetti M.R.,Moura-da-Silva A.M.,Oliva G.,Garratt R.C.,Souza D.H.F.
The three-dimensional structure of bothropasin, the main hemorrhagic factor from Bothrops jararaca venom: insights for a new classification of snake venom metalloprotease subgroups.
Toxicon
52
807-816
2008
