Sequence of Q93NH4_PAENI

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
(S)-6-hydroxynicotine oxidase
Q93NH4
Paenarthrobacter nicotinovorans
425
46335
Reaction
(S)-6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MYDAIVVGGG FSGLKAARDL TNAGKKVLLL EGGERLGGRA YSRESRNVPG LRVEIGGAYL
 60 HRKHHPRLAA ELDRYGIPTA AASEFTSFRH RLGPTAVDQA FPIPGSEAVA VEAATYTLLR
120 DAHRIDLEKG LENQDLEDLD IPLNEYVDKL DLPPVSRQFL LAWAWNMLGQ PADQASALWM
180 LQLVAAHHYS ILGVVLSLDE VFSNGSADLV DAMSQEIPEI RLQTVVTGID QSGDVVNVTV
240 KDGHAFQAHS VIVATPMNTW RRIVFTPALP ERRRSVIEEG HGGQGLKILI HVRGAEAGIE
300 CVGDGIFPTL YDYCEVSESE RLLVAFTDSG SFDPTDIGAV KDAVLYYLPE VEVLGIDYHD
360 WIADPLFEGP WVAPRVGQFS RVHKELGEPA GRIHFVGSDV SLEFPGYIEG ALETAECAVN
420 AILHS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
220350806
Brandsch R.,Hinkkanen A.E.,Mauch L.,Nagursky H.,Decker K.
6-hydroxy-D-nicotine oxidase of Arthrobacter oxidans. Gene structure of the flavoenzyme and its relationship to 6-hydroxy-L-nicotine oxidase.
Eur. J. Biochem.
167
315-320
1987
220350808
Baitsch D.,Sandu C.,Brandsch R.,Igloi G.L.
Gene cluster on pAO1 of Arthrobacter nicotinovorans involved in degradation of the plant alkaloid nicotine: cloning, purification, and characterization of 2,6-dihydroxypyridine 3-hydroxylase.
J. Bacteriol.
183
5262-5267
2001
220350809
Igloi G.L.,Brandsch R.
Sequence of the 165-kilobase catabolic plasmid pAO1 from Arthrobacter nicotinovorans and identification of a pAO1-dependent nicotine uptake system.
J. Bacteriol.
185
1976-1986
2003
220350810
Kachalova G.S.,Bourenkov G.P.,Mengesdorf T.,Schenk S.,Maun H.R.,Burghammer M.,Riekel C.,Decker K.,Bartunik H.D.
Crystal structure analysis of free and substrate-bound 6-hydroxy-L-nicotine oxidase from Arthrobacter nicotinovorans.
J. Mol. Biol.
396
785-799
2010
220350811
Kachalova G.,Decker K.,Holt A.,Bartunik H.D.
Crystallographic snapshots of the complete reaction cycle of nicotine degradation by an amine oxidase of the monoamine oxidase (MAO) family.
Proc. Natl. Acad. Sci. U.S.A.
108
4800-4805
2011
220350812
Mihasan M.,Brandsch R.
pAO1 of Arthrobacter nicotinovorans and the spread of catabolic traits by horizontal gene transfer in gram-positive soil bacteria.
J. Mol. Evol.
77
22-30
2013
220435249
Brandsch R.,Hinkkanen A.E.,Mauch L.,Nagursky H.,Decker K.
6-hydroxy-D-nicotine oxidase of Arthrobacter oxidans. Gene structure of the flavoenzyme and its relationship to 6-hydroxy-L-nicotine oxidase.
Eur. J. Biochem.
167
315-320
1987
220435251
Baitsch D.,Sandu C.,Brandsch R.,Igloi G.L.
Gene cluster on pAO1 of Arthrobacter nicotinovorans involved in degradation of the plant alkaloid nicotine: cloning, purification, and characterization of 2,6-dihydroxypyridine 3-hydroxylase.
J. Bacteriol.
183
5262-5267
2001
220435252
Igloi G.L.,Brandsch R.
Sequence of the 165-kilobase catabolic plasmid pAO1 from Arthrobacter nicotinovorans and identification of a pAO1-dependent nicotine uptake system.
J. Bacteriol.
185
1976-1986
2003
220435253
Kachalova G.S.,Bourenkov G.P.,Mengesdorf T.,Schenk S.,Maun H.R.,Burghammer M.,Riekel C.,Decker K.,Bartunik H.D.
Crystal structure analysis of free and substrate-bound 6-hydroxy-L-nicotine oxidase from Arthrobacter nicotinovorans.
J. Mol. Biol.
396
785-799
2010
220435254
Kachalova G.,Decker K.,Holt A.,Bartunik H.D.
Crystallographic snapshots of the complete reaction cycle of nicotine degradation by an amine oxidase of the monoamine oxidase (MAO) family.
Proc. Natl. Acad. Sci. U.S.A.
108
4800-4805
2011
220435255
Mihasan M.,Brandsch R.
pAO1 of Arthrobacter nicotinovorans and the spread of catabolic traits by horizontal gene transfer in gram-positive soil bacteria.
J. Mol. Evol.
77
22-30
2013