Sequence of MURG_ECOLI
EC Number:2.4.1.227
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
P17443
Escherichia coli (strain K12)
355
37815
Reaction
UDP-N-acetyl-alpha-D-glucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
Other sequences found for EC No. 2.4.1.227
General information:
Sequence
0 MSGQGKRLMV MAGGTGGHVF PGLAVAHHLM AQGWQVRWLG TADRMEADLV PKHGIEIDFI
60 RISGLRGKGI KALIAAPLRI FNAWRQARAI MKAYKPDVVL GMGGYVSGPG GLAAWSLGIP
120 VVLHEQNGIA GLTNKWLAKI ATKVMQAFPG AFPNAEVVGN PVRTDVLALP LPQQRLAGRE
180 GPVRVLVVGG SQGARILNQT MPQVAAKLGD SVTIWHQSGK GSQQSVEQAY AEAGQPQHKV
240 TEFIDDMAAA YAWADVVVCR SGALTVSEIA AAGLPALFVP FQHKDRQQYW NALPLEKAGA
300 AKIIEQPQLS VDAVANTLAG WSRETLLTMA ERARAASIPD ATERVANEVS RVARA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
62609
Ikeda M.,Wachi M.,Jung H.K.,Ishino F.,Matsuhashi M.
Nucleotide sequence involving murG and murC in the mra gene cluster region of Escherichia coli.
Nucleic Acids Res.
18
4014-4014
1990
62610
Yura T.,Mori H.,Nagai H.,Nagata T.,Ishihama A.,Fujita N.,Isono K.,Mizobuchi K.,Nakata A.
Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region.
Nucleic Acids Res.
20
3305-3308
1992
62611
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
62612
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
62613
Mengin-Lecreulx D.,Texier L.,van Heijenoort J.
Nucleotide sequence of the cell-envelope murG gene of Escherichia coli.
Nucleic Acids Res.
18
2810-2810
1990
62614
Mengin-Lecreulx D.,Texier L.,Rousseau M.,van Heijenoort J.
The murG gene of Escherichia coli codes for the UDP-N-acetylglucosamine: N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis.
J. Bacteriol.
173
4625-4636
1991
62615
Bupp K.,van Heijenoort J.
The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm.
J. Bacteriol.
175
1841-1843
1993
62616
Crouvoisier M.,Mengin-Lecreulx D.,van Heijenoort J.
UDP-N-acetylglucosamine:N-acetylmuramoyl-(pentapeptide) pyrophosphoryl undecaprenol N-acetylglucosamine transferase from Escherichia coli: overproduction, solubilization, and purification.
FEBS Lett.
449
289-292
1999
62617
Mohammadi T.,Karczmarek A.,Crouvoisier M.,Bouhss A.,Mengin-Lecreulx D.,den Blaauwen T.
The essential peptidoglycan glycosyltransferase MurG forms a complex with proteins involved in lateral envelope growth as well as with proteins involved in cell division in Escherichia coli.
Mol. Microbiol.
65
1106-1121
2007
62618
Ha S.,Walker D.,Shi Y.,Walker S.
The 1.9 A crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis.
Protein Sci.
9
1045-1052
2000
62619
Hu Y.,Chen L.,Ha S.,Gross B.,Falcone B.,Walker D.,Mokhtarzadeh M.,Walker S.
Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases.
Proc. Natl. Acad. Sci. U.S.A.
100
845-849
2003
