Sequence of YES_HUMAN
EC Number:2.7.10.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Other sequences found for EC No. 2.7.10.2
General information:
Sequence
0 MGCIKSKENK SPAIKYRPEN TPEPVSTSVS HYGAEPTTVS PCPSSSAKGT AVNFSSLSMT
60 PFGGSSGVTP FGGASSSFSV VPSSYPAGLT GGVTIFVALY DYEARTTEDL SFKKGERFQI
120 INNTEGDWWE ARSIATGKNG YIPSNYVAPA DSIQAEEWYF GKMGRKDAER LLLNPGNQRG
180 IFLVRESETT KGAYSLSIRD WDEIRGDNVK HYKIRKLDNG GYYITTRAQF DTLQKLVKHY
240 TEHADGLCHK LTTVCPTVKP QTQGLAKDAW EIPRESLRLE VKLGQGCFGE VWMGTWNGTT
300 KVAIKTLKPG TMMPEAFLQE AQIMKKLRHD KLVPLYAVVS EEPIYIVTEF MSKGSLLDFL
360 KEGDGKYLKL PQLVDMAAQI ADGMAYIERM NYIHRDLRAA NILVGENLVC KIADFGLARL
420 IEDNEYTARQ GAKFPIKWTA PEAALYGRFT IKSDVWSFGI LQTELVTKGR VPYPGMVNRE
480 VLEQVERGYR MPCPQGCPES LHELMNLCWK KDPDERPTFE YIQSFLEDYF TATEPQYQPG
540 ENL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
633660
Sukegawa J.,Semba K.,Yamanashi Y.,Nishizawa M.,Miyajima N.,Yamamoto T.,Toyoshima K.
Characterization of cDNA clones for the human c-yes gene.
Mol. Cell. Biol.
7
41-47
1987
633661
Nusbaum C.,Zody M.C.,Borowsky M.L.,Kamal M.,Kodira C.D.,Taylor T.D.,Whittaker C.A.,Chang J.L.,Cuomo C.A.,Dewar K.,FitzGerald M.G.,Yang X.,Abouelleil A.,Allen N.R.,Anderson S.,Bloom T.,Bugalter B.,Butler J.,Cook A.,DeCaprio D.,Engels R.,Garber M.,Gnirke A.,Hafez N.,Hall J.L.,Norman C.H.,Itoh T.,Jaffe D.B.,Kuroki Y.,Lehoczky J.,Lui A.,Macdonald P.,Mauceli E.,Mikkelsen T.S.,Naylor J.W.,Nicol R.,Nguyen C.,Noguchi H.,O'Leary S.B.,Piqani B.,Smith C.L.,Talamas J.A.,Topham K.,Totoki Y.,Toyoda A.,Wain H.M.,Young S.K.,Zeng Q.,Zimmer A.R.,Fujiyama A.,Hattori M.,Birren B.W.,Sakaki Y.,Lander E.S.
DNA sequence and analysis of human chromosome 18.
Nature
437
551-555
2005
633663
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
633664
Sugawara K.,Sugawara I.,Sukegawa J.,Akatsuka T.,Yamamoto T.,Morita M.,Mori S.,Toyoshima K.
Distribution of c-yes-1 gene product in various cells and tissues.
Br. J. Cancer
63
508-513
1991
633665
Krueger J.,Zhao Y.H.,Murphy D.,Sudol M.
Differential expression of p62c-yes in normal, hyperplastic and neoplastic human epidermis.
Oncogene
6
933-940
1991
633666
Koegl M.,Zlatkine P.,Ley S.C.,Courtneidge S.A.,Magee A.I.
Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif.
Biochem. J.
303
749-753
1994
633667
Sun G.,Budde R.J.
Expression, purification, and initial characterization of human Yes protein tyrosine kinase from a bacterial expression system.
Arch. Biochem. Biophys.
345
135-142
1997
633668
Sun G.,Sharma A.K.,Budde R.J.
Autophosphorylation of Src and Yes blocks their inactivation by Csk phosphorylation.
Oncogene
17
1587-1595
1998
633669
Lee S.W.,Bonnah R.A.,Higashi D.L.,Atkinson J.P.,Milgram S.L.,So M.
CD46 is phosphorylated at tyrosine 354 upon infection of epithelial cells by Neisseria gonorrhoeae.
J. Cell Biol.
156
951-957
2002
633670
Clump D.A.,Qazi I.H.,Sudol M.,Flynn D.C.
c-Yes response to growth factor activation.
Growth Factors
23
263-272
2005
633671
Martin N.G.,McAndrew P.C.,Eve P.D.,Garrett M.D.
Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases.
FEBS J.
275
3099-3109
2008
633672
Daub H.,Olsen J.V.,Bairlein M.,Gnad F.,Oppermann F.S.,Korner R.,Greff Z.,Keri G.,Stemmann O.,Mann M.
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
Mol. Cell
31
438-448
2008
633673
Dephoure N.,Zhou C.,Villen J.,Beausoleil S.A.,Bakalarski C.E.,Elledge S.J.,Gygi S.P.
A quantitative atlas of mitotic phosphorylation.
Proc. Natl. Acad. Sci. U.S.A.
105
10762-10767
2008
633674
Voss M.,Lettau M.,Janssen O.
Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.
BMC Immunol.
10
53-53
2009
633675
Varrin-Doyer M.,Vincent P.,Cavagna S.,Auvergnon N.,Noraz N.,Rogemond V.,Honnorat J.,Moradi-Ameli M.,Giraudon P.
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration.
J. Biol. Chem.
284
13265-13276
2009
633676
Sato I.,Obata Y.,Kasahara K.,Nakayama Y.,Fukumoto Y.,Yamasaki T.,Yokoyama K.K.,Saito T.,Yamaguchi N.
Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain.
J. Cell Sci.
122
965-975
2009
633677
Oppermann F.S.,Gnad F.,Olsen J.V.,Hornberger R.,Greff Z.,Keri G.,Mann M.,Daub H.
Large-scale proteomics analysis of the human kinome.
Mol. Cell. Proteomics
8
1751-1764
2009
633678
Jung J.,Lee M.K.,Jin Y.,Fu S.B.,Rosales J.L.,Lee K.Y.
Clues for c-Yes involvement in the cell cycle and cytokinesis.
Cell Cycle
10
1502-1503
2011
633679
Tauzin S.,Chaigne-Delalande B.,Selva E.,Khadra N.,Daburon S.,Contin-Bordes C.,Blanco P.,Le Seyec J.,Ducret T.,Counillon L.,Moreau J.F.,Hofman P.,Vacher P.,Legembre P.
The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.
PLoS Biol.
9
0-0
2011
633680
Taniguchi K.,Wu L.W.,Grivennikov S.I.,de Jong P.R.,Lian I.,Yu F.X.,Wang K.,Ho S.B.,Boland B.S.,Chang J.T.,Sandborn W.J.,Hardiman G.,Raz E.,Maehara Y.,Yoshimura A.,Zucman-Rossi J.,Guan K.L.,Karin M.
A gp130-Src-YAP module links inflammation to epithelial regeneration.
Nature
519
57-62
2015
633681
Martin-Garcia J.M.,Luque I.,Mateo P.L.,Ruiz-Sanz J.,Camara-Artigas A.
Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: loop flexibility and amyloid aggregation.
FEBS Lett.
581
1701-1706
2007
633682
Greenman C.,Stephens P.,Smith R.,Dalgliesh G.L.,Hunter C.,Bignell G.,Davies H.,Teague J.,Butler A.,Stevens C.,Edkins S.,O'Meara S.,Vastrik I.,Schmidt E.E.,Avis T.,Barthorpe S.,Bhamra G.,Buck G.,Choudhury B.,Clements J.,Cole J.,Dicks E.,Forbes S.,Gray K.,Halliday K.,Harrison R.,Hills K.,Hinton J.,Jenkinson A.,Jones D.,Menzies A.,Mironenko T.,Perry J.,Raine K.,Richardson D.,Shepherd R.,Small A.,Tofts C.,Varian J.,Webb T.,West S.,Widaa S.,Yates A.,Cahill D.P.,Louis D.N.,Goldstraw P.,Nicholson A.G.,Brasseur F.,Looijenga L.,Weber B.L.,Chiew Y.-E.,DeFazio A.,Greaves M.F.,Green A.R.,Campbell P.,Birney E.,Easton D.F.,Chenevix-Trench G.,Tan M.-H.,Khoo S.K.,Teh B.T.,Yuen S.T.,Leung S.Y.,Wooster R.,Futreal P.A.,Stratton M.R.
Patterns of somatic mutation in human cancer genomes.
Nature
446
153-158
2007
