Sequence of ACE2_RAT

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
angiotensin-converting enzyme 2
Q5EGZ1
Rattus norvegicus
805
92491
Reaction
angiotensin II + H2O = angiotensin-(1-7) + L-phenylalanine
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MSSSCWLLLS LVAVATAQSL IEEKAESFLN KFNQEAEDLS YQSSLASWNY NTNITEENAQ
 60 KMNEAAAKWS AFYEEQSKIA QNFSLQEIQN ATIKRQLKAL QQSGSSALSP DKNKQLNTIL
120 NTMSTIYSTG KVCNSMNPQE CFLLEPGLDE IMATSTDYNR RLWAWEGWRA EVGKQLRPLY
180 EEYVVLKNEM ARANNYEDYG DYWRGDYEAE GVEGYNYNRN QLIEDVENTF KEIKPLYEQL
240 HAYVRTKLME VYPSYISPTG CLPAHLLGDM WGRFWTNLYP LTTPFLQKPN IDVTDAMVNQ
300 SWDAERIFKE AEKFFVSVGL PQMTPGFWTN SMLTEPGDDR KVVCHPTAWD LGHGDFRIKM
360 CTKVTMDNFL TAHHEMGHIQ YDMAYAKQPF LLRNGANEGF HEAVGEIMSL SAATPKHLKS
420 IGLLPSNFQE DNETEINFLL KQALTIVGTL PFTYMLEKWR WMVFQDKIPR EQWTKKWWEM
480 KREIVGVVEP LPHDETYCDP ASLFHVSNDY SFIRYYTRTI YQFQFQEALC QAAKHDGPLH
540 KCDISNSTEA GQKLLNMLSL GNSGPWTLAL ENVVGSRNMD VKPLLNYFQP LFVWLKEQNR
600 NSTVGWSTDW SPYADQSIKV RISLKSALGK NAYEWTDNEM YLFRSSVAYA MREYFSREKN
660 QTVPFGEADV WVSDLKPRVS FNFFVTSPKN VSDIIPRSEV EEAIRMSRGR INDIFGLNDN
720 SLEFLGIYPT LKPPYEPPVT IWLIIFGVVM GTVVVGIVIL IVTGIKGRKK KNETKREENP
780 YDSMDIGKGE SNAGFQNSDD AQTSF
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
618736
Li W.,Greenough T.C.,Moore M.J.,Vasilieva N.,Somasundaran M.,Sullivan J.L.,Farzan M.,Choe H.
Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2.
J. Virol.
78
11429-11433
2004
618737
Crackower M.A.,Sarao R.,Oudit G.Y.,Yagil C.,Kozieradzki I.,Scanga S.E.,Oliveira-dos-Santos A.J.,da Costa J.,Zhang L.,Pei Y.,Scholey J.,Ferrario C.M.,Manoukian A.S.,Chappell M.C.,Backx P.H.,Yagil Y.,Penninger J.M.
Angiotensin-converting enzyme 2 is an essential regulator of heart function.
Nature
417
822-828
2002
618738
Douglas G.C.,O'Bryan M.K.,Hedger M.P.,Lee D.K.L.,Yarski M.A.,Smith A.I.,Lew R.A.
The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis.
Endocrinology
145
4703-4711
2004
618739
Burrell L.M.,Risvanis J.,Kubota E.,Dean R.G.,MacDonald P.S.,Lu S.,Tikellis C.,Grant S.L.,Lew R.A.,Smith A.I.,Cooper M.E.,Johnston C.I.
Myocardial infarction increases ACE2 expression in rat and humans.
Eur. Heart J.
26
369-375
2005
618740
Gembardt F.,Sterner-Kock A.,Imboden H.,Spalteholz M.,Reibitz F.,Schultheiss H.-P.,Siems W.-E.,Walther T.
Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents.
Peptides
26
1270-1277
2005