Sequence of LOXE3_HUMAN

hydroperoxy icosatetraenoate dehydratase

Q9BYJ1

711

80543

54629

Krieg P.,Marks F.,Fuerstenberger G.

A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression.

Genomics

73

323-330

2001

54630

Yu Z.,Schneider C.,Boeglin W.E.,Marnett L.J.,Brash A.R.

The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase.

Proc. Natl. Acad. Sci. U.S.A.

100

9162-9167

2003

54631

Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet.

36

40-45

2004

54633

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

54634

Yu Z.,Schneider C.,Boeglin W.E.,Brash A.R.

Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin.

Arch. Biochem. Biophys.

455

188-196

2006

54635

Zheng Y.,Brash A.R.

Dioxygenase activity of epidermal lipoxygenase-3 unveiled: typical and atypical features of its catalytic activity with natural and synthetic polyunsaturated fatty acids.

J. Biol. Chem.

285

39866-39875

2010

54636

Zheng Y.,Brash A.R.

On the role of molecular oxygen in lipoxygenase activation: comparison and contrast of epidermal lipoxygenase-3 with soybean lipoxygenase-1.

J. Biol. Chem.

285

39876-39887

2010

54637

Zheng Y.,Yin H.,Boeglin W.E.,Elias P.M.,Crumrine D.,Beier D.R.,Brash A.R.

Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope.

J. Biol. Chem.

286

24046-24056

2011

54638

Jobard F.,Lefevre C.,Karaduman A.,Blanchet-Bardon C.,Emre S.,Weissenbach J.,Ozguc M.,Lathrop M.,Prud'homme J.-F.,Fischer J.

Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1.

Hum. Mol. Genet.

11

107-113

2002

54639

Yu Z.,Schneider C.,Boeglin W.E.,Brash A.R.

Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3.

Biochim. Biophys. Acta

1686

238-247

2005

54640

Eckl K.M.,Krieg P.,Kuester W.,Traupe H.,Andre F.,Wittstruck N.,Fuerstenberger G.,Hennies H.C.

Mutation spectrum and functional analysis of epidermis-type lipoxygenases in patients with autosomal recessive congenital ichthyosis.

Hum. Mutat.

26

351-361

2005

54641

Eckl K.M.,de Juanes S.,Kurtenbach J.,Naetebus M.,Lugassy J.,Oji V.,Traupe H.,Preil M.L.,Martinez F.,Smolle J.,Harel A.,Krieg P.,Sprecher E.,Hennies H.C.

Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B.

J. Invest. Dermatol.

129

1421-1428

2009

54642

Vahlquist A.,Bygum A.,Gaanemo A.,Virtanen M.,Hellstroem-Pigg M.,Strauss G.,Brandrup F.,Fischer J.

Genotypic and clinical spectrum of self-improving collodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients.

J. Invest. Dermatol.

130

438-443

2010