Sequence of R1AB_CVMJH
EC Number:3.6.4.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
a nucleoside triphosphate + H2O = a nucleoside diphosphate + phosphate
Other sequences found for EC No. 3.6.4.13
General information:
Sequence
0 MAKMGKYGLG FKWAPEFPWM LPNASEKLGN PERSEEDGFC PSAAQEPKVK GKTLVNHVRV
60 DCSRLPALEC CVQSAIIRDI FVDEDPQKVE ASTMMALQFG SAVLVKPSKR LSVQAWAKLG
120 VLPKTPAMGL FKRFCLCNTR ECVCDAHVAF QLFTVQPDGV CLGNGRFIGW FVPVTAIPEY
180 AKQWLQPWSI LLRKGGNKGS VTSGHFRRAV TMPVYDFNVE DACEEVHLNP RGKYSCKAYA
240 LLRGYRGVKP ILFVDQYGCD YTGCLAKGLE DYGDLTLSEM KELSPVWRDS LDNEVVVAWH
300 VDRDPRAVMR LQTLATVRSI EYVGQPIEDM VDGDVVMREP AHLLAPNAIV KRLPRLVETM
360 LYTDSSVTEF CYKTKLCDCG FITQFGYVDC CGDTCGFRGW VPGNMMDGFP CPGCCKSYMP
420 WELEAQSSGV IPEGGVLFTQ STDTVNRESF KLYGHAVVPF GGAAYWSPYP GMWLPVIWSS
480 VKSYSYLTYT GVVGCKAIVQ ETDAICRFLY MDYVQHKCGN LEQRAILGLD DVYHRQLLVN
540 RGDYSLLLEN VDLFVKRRAE FACKFATCGD GLVPLLLDGL VPRSYYLIKS GQAFTSLMVN
600 FSREVVDMCM DMALLFMHDV KVATKYVKKV TGKVAVRFKA LGIAVVRKIT EWFDLAVDTA
660 ASAAGWLCYQ LVNGLFAVAN GVITFIQEVP ELVKNFVDKF KTFFKVLIDS MSVSILSGLT
720 VVKTASNRVC LAGSKVYEVV QKSLPAYIMP VGCSEATCLV GEIEPAVFED DVVDVVKAPL
780 TYQGCCKPPS SFEKICIVDK LYMAKCGDQF YPVVVDNDTV GVLDQCWRFP CAGKKVVFND
840 KPKVKEVPST RKIKIIFALD ATFDSVLSKA CSEFEVDKDV TLDELLDVVL DAVESTLSPC
900 KEHGVIGTKV CALLERLVDD YVYLFDEGGE EVIASRMYCS FSAPDEDCVA TDVVYADENQ
960 DDDADDPVVL VADTQEEDGV AREQVDSADS EICVAHTGGQ EMTEPDVVGS QTPIASAEET
1020 EVGEACDREG IAEVKATVCA DALDACPDQV EAFDIEKVED SILSELQTEL NAPADKTYED
1080 VLAFDAIYSE TLSAFYAVPS DETHFKVCGF YSPAIERTNC WLRSTLIVMQ SLPLEFKDLG
1140 MQKLWLSYKA GYDQCFVDKL VKSAPKSIIL PQGGYVADFA YFFLSQCSFK VHANWRCLKC
1200 GMELKLQGLD AVFFYGDVVS HMCKCGNSMT LLSADIPYTF DFGVRDDKFC AFYTPRKVFR
1260 AACAVDVNDC HSMAVVDGKQ IDGKVVTKFN GDKFDFMVGH GMTFSMSPFE IAQLYGSCIT
1320 PNVCFVKGDV IKVLRRVGAE VIVNPANGRM AHGAGVAGAI AKAAGKAFIN ETADMVKAQG
1380 VCQVGGCYES TGGKLCKKVL NIVGPDARGH GNECYSLLER AYQHINKCDN VVTTLISAGI
1440 FSVPTDVSLT YLLGVVTKNV ILVSNNQDDF DVIEKCQVTS VAGTKALSFQ LAKNLCRDVK
1500 FVTNACSSLF SESSFVSSYD VLQEVEALRH DIQLDDDARV FVQANMDCLP TDWRLVNKFD
1560 SVDGVRTIKY FECPGEVFVS SQGKKFGYVQ NGSFKEASVS QIRALLANKV DVLCTVDGVN
1620 FRSCCVAEGE VFGKTLGSVF CDGINVTKVR CSAIHKGKVF FQYSGLSAAD LAAVKDAFGF
1680 DEPQLLQYYS MLGMCKWPVV VCGNYFAFKQ SNNNCYINVA CLMLQHLSLK FPKWQWRRPG
1740 NEFRSGKPLR FVSLVLAKGS FKFNEPSDST DFIRVELREA DLSGATCDLE FICKCGVKQE
1800 QRKGVDAVMH FGTLDKSGLV KGYNIACTCG DKLVHCTQFN VPFLICSNTP EGKKLPDDVV
1860 AANIFTGGSV GHYTHVKCKP KYQLYDACNV SKVSEAKGNF TDCLYLKNLK QTFSSVLTTY
1920 YLDDVKCVAY KPDLSQYYCE SGKYYTKPII KAQFRTFEKV EGVYTNFKLV GHDIAEKLNA
1980 KLGFDCNSPF MEYKITEWPT ATGDVVLASD DLYVSRYSGG CVTFGKPVIW RGHEEASLKS
2040 LTYFNRPSVV CENKFNVLPV DVSEPTDRRP VPSAVLVTGA ASGADASAIS TEPGTAKEQK
2100 ACASDSVEDQ IVMEAQKKSS VTTVAVKEVK LNGVKKPVKW NCSVVVNDPT SETKVVKSLS
2160 IVDVYDMFLT GCRYVVWTAN ELSRLINSPT VREYVKWGMS KLIIPANLLL LRDEKQEFVA
2220 PKVVKAKAIA CYGAVKWFLL YCFSWIKFNT DNKVIYTTEV ASKLTFKLCC LAFKNALQTF
2280 NWSVVSRGFF LVATVFLLWF NFLYANVILS DFYLPNIGPL PMFVGQIVAW VKTTFGVLTI
2340 CDFYQVTDLG YRSSFCNGSM VCELCFSGFD MLDNYESINV VQHVVDRRVS FDYISLFKLV
2400 VELVIGYSLY TVCFYPLFVL VGMQLLTTWL PEFFMLGTMH WSARLFVFVA NMLPAFTLLR
2460 FYIVVTAMYK VYCLCRHVMY GCSKPGCLFC YKRNRSVRVK CSTVVGGSLR YYDVMANGGT
2520 GFCTKHQWNC LNCNSWKPGN TFITHEAAAD LSKELKRPVN PTDSAYYSVI EVKQVGCSMR
2580 LFYERDGQRV YDDVSASLFV DMNGLLHSKV KGVPETHVVV VENEADKAGF LNAAVFYAQS
2640 LYRPMLMVEK KLITTANTGL SVSRTMFDLY VYSLLRHLDV DRKSLTSFVN AAHNSLKEGV
2700 QLEQVMDTFV GCARRKCAID SDVETKSITK SVMAAVNAGV EVTDESCNNL VPTYVKSDTI
2760 VAADLGVLIQ NNAKHVQSNV AKAANVACIW SVDAFNQLSA DLQHRLRKAC VKTGLKIKLT
2820 YNKQEANVPI LTTPFSLKGG AVFSRVLQWL FVANLICFIV LWALMPTYAV HKSDMQLPLY
2880 ASFKVIDNGV LRDVSVTDAC FANKFNQFDQ WYESTFGLVY YRNSKACPVV VAVIDQDIGH
2940 TLFNVPTKVL RYGFHVLHFI THAFATDRVQ CYTPHMQIPY DNFYASGCVL SSLCTMLAHA
3000 DGTPHPYCYT EGVMHNASLY SSLVPHVRYN LASSNGYIRF PEVVSEGIVR VVRTRSMTYC
3060 RVGLCEEAEE GICFNFNSSW VLNNPYYRAM PGTFCGRNAF DLIHQVLGGL VQPIDFFALT
3120 ASSVAGAILA IIVVLAFYYL IKLKRAFGDY TSVVVINVIV WCINFLMLFV FQVYPTLSCL
3180 YACFYFYTTL YFPSEISVVM HLQWLVMYGA IMPLWFCITY VAVVVSNHAL WLFSYCRKIG
3240 TDVRSDGTFE EMALTTFMIT KESYCKLKNS VSDVAFNRYL SLYNKYRYFS GKMDTATYRE
3300 AACSQLAKAM ETFNHNNGND VLYQPPTASV TTSFLQSGIV KMVSPTSKVE PCVVSVTYGN
3360 MTLNGLWLDD KVYCPRHVIC SSADMTDPDY PNLLCRVTSS DFCVMSDRMS LTVMSYQMQG
3420 SLLVLTVTLQ NPNTPKYSFG VVKPGETFTV LAAYNGRPQG AFHVVMRSSH TIKGSFLCGS
3480 CGSVGYVLTG DSVRFVYMHQ LELSTGCHTG TDFSGNFYGP YRDAQVVQLP VQDYTQTVNV
3540 VAWLYAAILN RCNWFVQSDS CSLEEFNVWA MTNGFSSIKA DLVLDALASM TGVTVEQVLA
3600 AIKRLHSGFQ GKQILGSCVL EDELTPSDVY QQLAGVKLQS KRTRVIKGTC CWILASTFLF
3660 CSIISAFVKW TMFMYVTTHM LGVTLCALCF VIFAMLLIKH KHLYLTMYIM PVLCTLFYTN
3720 YLVVGYKQSF RGLAYAWLSY FVPAVDYTYM DEVLYGVVLL VAMVFVTMRS INHDVFSTMF
3780 LVGRLVSLVS MWYFGANLEE EVLLFLTSLF GTYTWTTMLS LATAKVIAKW LAVNVLYFTD
3840 IPQIKLVLLS YLCIGYVCCC YWGVLSLLNS IFRMPLGVYN YKISVQELRY MNANGLRPPR
3900 NSFEALMLNF KLLGIGGVPV IEVSQIQSRL TDVKCANVVL LNCLQHLHIA SNSKLWQYCS
3960 TLHNEILATS DLSVAFDKLA QLLVVLFANP AAVDSKCLAS IEEVSDDYVR DNTVLQALQS
4020 EFVNMASFVE YELAKKNLDE AKASGSANQQ QIKQLEKACN IAKSAYERDR AVARKLERMA
4080 DLALTNMYKE ARINDKKSKV VSALQTMLFS MVRKLDNQAL NSILDNAVKG CVPLNAIPPL
4140 TSNTLTIIVP DKQVFDQVVD NVYVTYAPNV WHIQSIQDAD GAVKQLNEID VNSTWPLVIS
4200 ANRHNEVSTV VLQNNELMPQ KLRTQVVNSG SDMNCNIPTQ CYYNTTGTGK IVYAILSDCD
4260 GLKYTKIVKE DGNCVVLELD PPCKFSVQDV KGLKIKYLYF VKGCNTLARG WVVGTLSSTV
4320 RLQAGTATEY ASNSAILSLC AFSVDPKKTY LDYIQQGGVP VTNCVKMLCD HAGTGMAITI
4380 KPEATTNQDS YGGASVCIYC RSRVEHPDVD GLCKLRGKFV QVPLGIKDPV SYVLTHDVCQ
4440 VCGFWRDGSC SCVGTGSQFQ SKDTNFLNRV RGTSVNARLV PCASGLDTDV QLRAFDICNA
4500 NRAGIGLYYK VNCFRFQRVD EEGNKLDKFF VVKRTNLEVY NKEKECYELT KDCGVVAEHE
4560 FFTFDVEGSR VPHIVRKDLS KFTMLDLCYA LRHFDRNDCS TLKEILLTYA ECDESYFQKK
4620 DWYDFVENPD IINVYKKLGP IFNRALLNTA NFADTLVEAG LVGVLTLDNQ DLYGQWYDFG
4680 DFVKTVPCCG VAVADSYYSY MMPMLTMCHA LDSELFVNGT YREFDLVQYD FTDFKLELFN
4740 KYFKHWSMTY HPNTSECEDD RCIIHCANFN ILFSMVLPKT CFGPLVRQIF VDGVPFVVSI
4800 GYHYKELGVV MNMDVDTHRY RLSLKDLLLY AADPALHVAS ASALLDLRTC CFSVAAITSG
4860 VKFQTVKPGN FNQDFYEFIL SKGLLKEGSS VDLKHFFFTQ DGNAAITDYN YYKYNLPTMV
4920 DIKQLLFVVE VVNKYFEIYE GGCIPATQVI VNNYDKSAGY PFNKFGKARL YYEALSFEEQ
4980 DEIYAYTKRN VLPTLTQMNL KYAISAKNRA RTVAGVSILS TMTGRMFHQK CLKSIAATRG
5040 VPVVIGTTKF YGGWDDMLRR LIKDVDSPVL MGWDYPKCDR AMPNILRIVS SLVLARKHDS
5100 CCSHTDRFYR LANECAQVLG EIVMCGGCYY VKPGGTSSGD ATTAFANSVF NICQAVSANV
5160 CSLMACNGHK IEDLSIRELQ KRLYSNVYRA DHVDPAFVSE YYEFLNKHFS MIILSDDGVV
5220 CYNSEFASKG YIANISDFQQ VLYYQNNVFM SEAKCWVETD IEKGPHEFCS QHTMLVKMDG
5280 DEVYLPYPDP SRILGAGCFV DDLLKTDSVL LIERFVSLAI DAYPLVYHEN PEYQNVFRVY
5340 LEYIKKLYND LGNQILDSIS VILSTCDGQK FTDETFYKNM YLRSAVMQSV GACVVCSSQT
5400 SLRCGSCIRK PLLCCKCAYD HVMSTDHKYV LSVSPYVCNS PGCDVNDVTK LYLGGMSYYC
5460 EAHKPQYSFK LVMNGMVFGL YKQSCTGSPY IEDFNKIASC KWTEVDDYVL ANECTERLKL
5520 FAAETQKATE EAFKQCYASA TIREIVSDRE LILSWEIGKV RPPLNKNYVF TGYHFTNNGK
5580 TVLGEYVFDK SELTNGVYYR ATTTYKLSVG DVFILTSHAV SSLSAPTLVP QENYTSVRFA
5640 SAYSVPETFQ NNVPNYQHIG IKRYCTVQGP PGTGKSHLAI GHAVYYCTAR VVYTAASHAA
5700 VDALCEKAHK FLNINDCARI VPAKLRVDCY DKFNVNDTTR KYVFTTINAL PELVTDIIVV
5760 DEVSMLTNYE LSVINSRVRA KHYVYIGDPA QLPAPRVLLN KGTLEPRYFN SVTKLMCCLG
5820 PDIFLGTCYR CPKEIVDTVS ALVYNNKLKA KNDNSAMCFK VYYKGQTTHE SSSAVNMQQI
5880 HLISKLLKAN PSWSNAVFIS PYNSQNYVAK RVLGLQTQTA DSAQGSAYDF VIYSQTAQTA
5940 HSVNVNRFNV AITRAKKGIL CVMSSMQLIG VFNFTTLTLD KINNPRLQCT TNLFKDCSKS
6000 YVGIPPCAFL LAVDDKYKVS GNLAVCLNVA DSAVTYSRLI SLMGFKLDLT LDGYCKLFIT
6060 RDEAIKRVRA WVGFDAEGAH ATRDSIGTNF PLQLGFSTGI DFVVEATGMF AERDGYVFKK
6120 AAARAPPGEQ FKHLVPLMSR GQKWDVVRIR IVQMLSDHLV DLADSVVLVT WAASFELTCL
6180 RYFAKVGKEV VCSVCNKRAT CFNSRTGYYG CWRHSYSCDY LYNPLIVDIQ QWGYTGSLTS
6240 NHDPICSVHK GAHVASSDAI MTRCLAVHDC FCKSVNWNLE YPIISNEVSV NTSCRLLQRV
6300 MFRAAMLCNR YDVCYDIGNP KGLACVKGYD FKFYDASPVV KSVKQFVYKY EAHKDQFLDG
6360 LCMFWNCNVD KYPANAVVCR FDTRVLSKLN LPGCNGGSLY VNKHAFHTNP FTRAAFENLK
6420 PMPFFYYSDT PCVYMEGMES KQVDYVPLRS ATCITRCNLG GAVCLKHAEE YREYLESYNT
6480 ATTAGFTFWV YKTFDFYNLW NTFTRLQSLE NVVYNLVNAG HFDGRAGELP CAVIGEKVIA
6540 KIQNEDVVVF KNNTPFPTNV AVELFAERSI RPHPELKLFR SSNIHVCWNH VLWDYAKDSV
6600 FCSSTYKVCK YTDLQCIESL NVLFDGRDNG ALEAFKKCRN GVYINTTKIK SLSMIKGPQR
6660 ADLNGVVVEK VGDSDVEFWF AMRRDGDDVI FSRTGSLEPS HYRSPQGNPG GNRVGDLSGN
6720 EALARGTIFT QSRFLSSFSP RSEMEKDFMD LDEDVFIAKY SLQDYAFEHV VYGSFNQKII
6780 GGLHLLIGLA RRPKKSNLVI QEFVPYDSSI HSYFITDENS GSSESVCTVI DLLLDDFVDI
6840 VKSLNLKCVS KVVNVNVDFK DFQFMLWCNE EKVMTFYPRL QAAADWKPGY VMPVLYKYLE
6900 SPMERVNLWN YGKPITLPTG CMMNVAKYTQ LCQYLSTTTL AVPANMRVLH LGAGSDKGVA
6960 PGSAVLRQWL PSGSILVDND MNPFVSDSVA SYYGNCITLP FDCQWDLIIS DMYDPLTKNI
7020 GEYNVSKDGF FTYLCHLIRD KLALGGSVAI KITEFSWNAE LYSLMGKFAF WTIFCTNVNA
7080 SSSEGFLIGI NWLNRTRNEI DGKTMHANYL FWRNSTMWNG GAYSLFDMTK FPLKAAGTAV
7140 VSLKPDQIND LVLSLIEKGK LLVRDTRKEV FVGDSLVNVK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
594263
Lee H.-J.,Shieh C.-K.,Gorbalenya A.E.,Koonin E.V.,la Monica N.,Tuler J.,Bagdzhardzhyan A.,Lai M.M.C.
The complete sequence (22 kilobases) of murine coronavirus gene 1 encoding the putative proteases and RNA polymerase.
Virology
180
567-582
1991
594264
Soe L.H.,Shieh C.-K.,Baker S.C.,Chang M.F.,Lai M.M.C.
Sequence and translation of the murine coronavirus 5'-end genomic RNA reveals the N-terminal structure of the putative RNA polymerase.
J. Virol.
61
3968-3976
1987
594265
Bonilla P.J.,Gorbalenya A.E.,Weiss S.R.
Mouse hepatitis virus strain A59 RNA polymerase gene ORF 1a: heterogeneity among MHV strains.
Virology
198
736-740
1994
594266
Baker S.C.,La Monica N.,Shieh C.K.,Lai M.M.
Murine coronavirus gene 1 polyprotein contains an autoproteolytic activity.
Adv. Exp. Med. Biol.
276
283-289
1990
594267
Kanjanahaluethai A.,Jukneliene D.,Baker S.C.
Identification of the murine coronavirus MP1 cleavage site recognized by papain-like proteinase 2.
J. Virol.
77
7376-7382
2003
594268
Schiller J.J.,Kanjanahaluethai A.,Baker S.C.
Processing of the coronavirus MHV-JHM polymerase polyprotein: identification of precursors and proteolytic products spanning 400 kilodaltons of ORF1a.
Virology
242
288-302
1998
594269
Hegyi A.,Ziebuhr J.
Conservation of substrate specificities among coronavirus main proteases.
J. Gen. Virol.
83
595-599
2002
