Sequence of PAGL_PSEAE
EC Number:3.1.1.77
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
acyloxyacyl hydrolase
Q9HVD1
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
173
18394
Reaction
3-(acyloxy)acyl group of bacterial toxin + H2O = 3-hydroxyacyl group of bacterial toxin + a fatty acid
Other sequences found for EC No. 3.1.1.77
General information:
Sequence
0 MKKLLPLAVL AALSSVHVAS AQAADVSAAV GATGQSGMTY RLGLSWDWDK SWWQTSTGRL
60 TGYWDAGYTY WEGGDEGAGK HSLSFAPVFV YEFAGDSIKP FIEAGIGVAA FSGTRVGDQN
120 LGSSLNFEDR IGAGLKFANG QSVGVRAIHY SNAGLKQPND GIESYSLFYK IPI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
582409
Stover C.K.,Pham X.-Q.T.,Erwin A.L.,Mizoguchi S.D.,Warrener P.,Hickey M.J.,Brinkman F.S.L.,Hufnagle W.O.,Kowalik D.J.,Lagrou M.,Garber R.L.,Goltry L.,Tolentino E.,Westbrock-Wadman S.,Yuan Y.,Brody L.L.,Coulter S.N.,Folger K.R.,Kas A.,Larbig K.,Lim R.M.,Smith K.A.,Spencer D.H.,Wong G.K.-S.,Wu Z.,Paulsen I.T.,Reizer J.,Saier M.H. Jr.,Hancock R.E.W.,Lory S.,Olson M.V.
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.
Nature
406
959-964
2000
582410
Geurtsen J.,Steeghs L.,Hove J.T.,van der Ley P.,Tommassen J.
Dissemination of lipid A deacylases (pagL) among gram-negative bacteria: identification of active-site histidine and serine residues.
J. Biol. Chem.
280
8248-8259
2005
582411
Ernst R.K.,Adams K.N.,Moskowitz S.M.,Kraig G.M.,Kawasaki K.,Stead C.M.,Trent M.S.,Miller S.I.
The Pseudomonas aeruginosa lipid A deacylase: selection for expression and loss within the cystic fibrosis airway.
J. Bacteriol.
188
191-201
2006
582412
Rutten L.,Geurtsen J.,Lambert W.,Smolenaers J.J.,Bonvin A.M.,de Haan A.,van der Ley P.,Egmond M.R.,Gros P.,Tommassen J.
Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa.
Proc. Natl. Acad. Sci. U.S.A.
103
7071-7076
2006
