Sequence of MYCE_MICGR
EC Number:2.1.1.238
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
S-adenosyl-L-methionine + mycinamicin VI = S-adenosyl-L-homocysteine + mycinamicin III
Other sequences found for EC No. 2.1.1.238
General information:
Sequence
0 MTAQTEFDEA TVQDVVRLAG GHDSELRELT QKYDPAMISR LLVAEILSRC PPPSNDTPVL
60 VELAIVHGSE RFRHFLRVVR DSPIRPVGAD EGFVGMLVEY ELTELLRELF GVTHERPAGV
120 RGTKLFPYLT DDEEAVEQIG TYLLAAQQGT EAVLAGCGSR KPDLSELSSR YFTPKFGFLH
180 WFTPHYDRHF RDYRNQQVRV LEIGVGGYKH PEWGGGSLRM WKSFFPRGQI YGLDIMDKSH
240 VDELRIRTIQ GDQNDAEFLD RIARRYGPFD IVIDDGSHIN AHVRTSFAAL FPHVRPGGLY
300 VIEDMWTAYW PGFGGQADPQ ECSGTSLGLL KSLIDAIQHQ ELPSDPNRSP GYVDRNIVGL
360 HVYHNVAFVE KGRNDEGGIP TWIPRDFESL VQASSGGAT
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
573717
Anzai Y.,Saito N.,Tanaka M.,Kinoshita K.,Koyama Y.,Kato F.
Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.
FEMS Microbiol. Lett.
218
135-141
2003
573718
Li S.,Anzai Y.,Kinoshita K.,Kato F.,Sherman D.H.
Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics.
ChemBioChem
10
1297-1301
2009
573719
Tsukada S.,Anzai Y.,Li S.,Kinoshita K.,Sherman D.H.,Kato F.
Gene targeting for O-methyltransferase genes, mycE and mycF, on the chromosome of Micromonospora griseorubida producing mycinamicin with a disruption cassette containing the bacteriophage phi C31 attB attachment site.
FEMS Microbiol. Lett.
304
148-156
2010
573720
Akey D.L.,Li S.,Konwerski J.R.,Confer L.A.,Bernard S.M.,Anzai Y.,Kato F.,Sherman D.H.,Smith J.L.
A new structural form in the SAM/metal-dependent o-methyltransferase family: MycE from the mycinamicin biosynthetic pathway.
J. Mol. Biol.
413
438-450
2011
