Sequence of ERBB4_MOUSE
EC Number:2.7.10.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Other sequences found for EC No. 2.7.10.1
General information:
Sequence
0 MKLATGLWVW GSLLMAAGTV QPSASQSVCA GTENKLSSLS DLEQQYRALR KYYENCEVVM
60 GNLEITSIEH NRDLSFLRSI REVTGYVLVA LNQFRYLPLE NLRIIRGTKL YEDRYALAIF
120 LNYRKDGNFG LQELGLKNLT EILNGGVYVD QNKFLCYADT IHWQDIVRNP WPSNMTLVST
180 NGSSGCGRCH KSCTGRCWGP TENHCQTLTR TVCAEQCDGR CYGPYVSDCC HRECAGGCSG
240 PKDTDCFACM NFNDSGACVT QCPQTFVYNP TTFQLEHNFN AKYTYGAFCV KKCPHNFVVD
300 SSSCVRACPS SKMEVEENGI KMCKPCTDIC PKACDGIGTG SLMSAQTVDS SNIDKFINCT
360 KINGNLIFLV TGIHGDPYNA IDAIDPEKLN VFRTVREITG FLNIQSWPPN MTDFSVFSNL
420 VTIGGRVLYS GLSLLILKQQ GITSLQFQSL KEISAGNIYI TDNSNLCYYH TINWTTLFST
480 INQRIVIRDN RRAENCTAEG MVCNHLCSND GCWGPGPDQC LSCRRFSRGK ICIESCNLYD
540 GEFREFENGS ICVECDSQCE KMEDGLLTCH GPGPDNCTKC SHFKDGPNCV EKCPDGLQGA
600 NSFIFKYADQ DRECHPCHPN CTQGCNGPTS HDCIYYPWTG HSTLPQHART PLIAAGVIGG
660 LFILVIMALT FAVYVRRKSI KKKRALRRFL ETELVEPLTP SGTAPNQAQL RILKETELKR
720 VKVLGSGAFG TVYKGIWVPE GETVKIPVAI KILNETTGPK ANVEFMDEAL IMASMDHPHL
780 VRLLGVCLSP TIQLVTQLMP HGCLLDYVHE HKDNIGSQLL LNWCVQIAKG MMYLEERRLV
840 HRDLAARNVL VKSPNHVKIT DFGLARLLEG DEKEYNADGG KMPIKWMALE CIHYRKFTHQ
900 SDVWSYGVTI WELMTFGGKP YDGIPTREIP DLLEKGERLP QPPICTIDVY MVMVKCWMID
960 ADSRPKFKEL AAEFSRMARD PQRYLVIQGD DRMKLPSPND SKFFQNLLDE EDLEDMMDAE
1020 EYLVPQAFNI PPPIYTSRTR IDSNRSEIGH SPPPAYTPMS GNQFVYQDGG FATQQGMPMP
1080 YRATTSTIPE APVAQGATAE MFDDSCCNGT LRKPVAPHVQ EDSSTQRYSA DPTVFAPERN
1140 PRGELDEEGY MTPMHDKPKQ EYLNPVEENP FVSRRKNGDL QALDNPEYHS ASSGPPKAED
1200 EYVNEPLYLN TFANALGSAE YMKNSVLSVP EKAKKAFDNP DYWNHSLPPR STLQHPDYLQ
1260 EYSTKYFYKQ NGRIRPIVAE NPEYLSEFSL KPGTMLPPPP YRHRNTVV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
541181
Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.
Lineage-specific biology revealed by a finished genome assembly of the mouse.
PLoS Biol.
7
0-0
2009
541182
Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.
The transcriptional landscape of the mammalian genome.
Science
309
1559-1563
2005
541183
Elenius K.,Corfas G.,Paul S.,Choi C.J.,Rio C.,Plowman G.D.,Klagsbrun M.
A novel juxtamembrane domain isoform of HER4/ErbB4. Isoform-specific tissue distribution and differential processing in response to phorbol ester.
J. Biol. Chem.
272
26761-26768
1997
541184
Moscoso L.M.,Chu G.C.,Gautam M.,Noakes P.G.,Merlie J.P.,Sanes J.R.
Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle.
Dev. Biol.
172
158-169
1995
541186
Gassmann M.,Casagranda F.,Orioli D.,Simon H.,Lai C.,Klein R.,Lemke G.
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor.
Nature
378
390-394
1995
541187
Jones F.E.,Welte T.,Fu X.Y.,Stern D.F.
ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation.
J. Cell Biol.
147
77-88
1999
541188
Elenius K.,Choi C.J.,Paul S.,Santiestevan E.,Nishi E.,Klagsbrun M.
Characterization of a naturally occurring ErbB4 isoform that does not bind or activate phosphatidyl inositol 3-kinase.
Oncogene
18
2607-2615
1999
541189
Golding J.P.,Trainor P.,Krumlauf R.,Gassmann M.
Defects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4.
Nat. Cell Biol.
2
103-109
2000
541190
Long W.,Wagner K.U.,Lloyd K.C.,Binart N.,Shillingford J.M.,Hennighausen L.,Jones F.E.
Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.
Development
130
5257-5268
2003
541191
Tidcombe H.,Jackson-Fisher A.,Mathers K.,Stern D.F.,Gassmann M.,Golding J.P.
Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality.
Proc. Natl. Acad. Sci. U.S.A.
100
8281-8286
2003
541192
Anton E.S.,Ghashghaei H.T.,Weber J.L.,McCann C.,Fischer T.M.,Cheung I.D.,Gassmann M.,Messing A.,Klein R.,Schwab M.H.,Lloyd K.C.,Lai C.
Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain.
Nat. Neurosci.
7
1319-1328
2004
541193
Clark D.E.,Williams C.C.,Duplessis T.T.,Moring K.L.,Notwick A.R.,Long W.,Lane W.S.,Beuvink I.,Hynes N.E.,Jones F.E.
ERBB4/HER4 potentiates STAT5A transcriptional activity by regulating novel STAT5A serine phosphorylation events.
J. Biol. Chem.
280
24175-24180
2005
541194
Linggi B.,Carpenter G.
ErbB-4 s80 intracellular domain abrogates ETO2-dependent transcriptional repression.
J. Biol. Chem.
281
25373-25380
2006
541195
Muraoka-Cook R.S.,Sandahl M.,Husted C.,Hunter D.,Miraglia L.,Feng S.M.,Elenius K.,Earp H.S. III
The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells.
Mol. Biol. Cell
17
4118-4129
2006
541196
Muraoka-Cook R.S.,Sandahl M.A.,Strunk K.E.,Miraglia L.C.,Husted C.,Hunter D.M.,Elenius K.,Chodosh L.A.,Earp H.S. III
ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo.
Mol. Cell. Biol.
29
4935-4948
2009
541197
Bersell K.,Arab S.,Haring B.,Kuhn B.
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury.
Cell
138
257-270
2009
541198
Jones F.E.,Golding J.P.,Gassmann M.
ErbB4 signaling during breast and neural development: novel genetic models reveal unique ErbB4 activities.
Cell Cycle
2
555-559
2003
541199
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
541200
Rico B.,Marin O.
Neuregulin signaling, cortical circuitry development and schizophrenia.
Curr. Opin. Genet. Dev.
21
262-270
2011
