Sequence of AAC6_SALEN

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
aminoglycoside 6'-N-acetyltransferase
Q9R381
Salmonella enteritidis
145
16362
Reaction
acetyl-CoA + kanamycin-B = CoA + N6'-acetylkanamycin-B
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MDIRQMNKTH LEHWRGLRKQ LWPGHPDDAH LADGEEILQA DHLASFIAMA DGVAIGFADA
 60 SIRHDYVNGC DSSPVVFLEG IFVLPSFRQR GVAKQLIAAV QRWGTNKGCR EMASDTSPEN
120 TISQKVHQAL GFEETERVIF YRKRC
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
758
Magnet S.,Courvalin P.,Lambert T.
Activation of the cryptic aac(6')-Iy aminoglycoside resistance gene of Salmonella by a chromosomal deletion generating a transcriptional fusion.
J. Bacteriol.
181
6650-6655
1999
759
Vetting M.W.,Magnet S.,Nieves E.,Roderick S.L.,Blanchard J.S.
A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones.
Chem. Biol.
11
565-573
2004
760
Magalhaes M.L.,Vetting M.W.,Gao F.,Freiburger L.,Auclair K.,Blanchard J.S.
Kinetic and structural analysis of bisubstrate inhibition of the Salmonella enterica aminoglycoside 6'-N-acetyltransferase.
Biochemistry
47
579-584
2008