Sequence of CHS6_CRYNH
EC Number:2.4.1.16
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
chitin synthase
J9VWT0
Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
944
104522
Reaction
UDP-N-acetyl-alpha-D-glucosamine + [(1->4)-N-acetyl-beta-D-glucosaminyl]n = UDP + [(1->4)-N-acetyl-beta-D-glucosaminyl]n+1
Other sequences found for EC No. 2.4.1.16
General information:
Sequence
0 MPNISRKPPP RFYSPSHSPS PSLYAPIQSP PAPSYDYHAN PRTLNPFSDA REVGGYAQLQ
60 GEDQMTGAPL YQPPYAPQLL VAQPTPVSSR LPFFEAALAR ARGIQTPSLP EAPTPAYAQP
120 LPSYLPPPDP NHPDLSVGLT QANTVRYAIN PRSQLKEGSR SPSPFMDDSF VYNDAAHLYN
180 VEPDVEKALL GSGLGYESEK RVESSMGFND NDGDLSVPQS FGGRPPSWEP SGILDEKGEM
240 STTKHFGPAP AGRVGRRAHN AAGYRRIKQS ATLDENGFFA IEMNIPTRLA QFLPIKGVEE
300 QKTTRYTAIT TDPDDVPAAG FRLRQNMTSP PRQTELFIVI TMYNENAELF CRTLYGVMKN
360 IAHLCGRKNS RVWGKDGWQK VVVCIVADGR KAVNPRVLDC LAALGVYQEG AMTNTVKDRP
420 VTAHVFEYTT SFALDGDLHF KYPDKGIVPC QIIFCMKEKN AKKINSHRWF FNAFAPLLSP
480 NVCILLDVGT QPAPKSIYHL WKAFDVNSNV GGACGEIATF KGKTWRSLLN PLVAAQAFEY
540 KMSNILDKPL ESLFGYCTVL PGAFSAYRWI ALQNNGDGRT GPLASYFAGE QLNTGKADTF
600 TGNITWQKIE SCVSKSAKPK ANWVLKFVKA AVGETDCPDT IPEFIAQRRR WLNGSFFAAV
660 YALMHTNQIW RSDHSFARKS ALMLESVYNF LNLIFSWFAL ANFYIFFVIL TSALEGSAFN
720 VPHIDVLNTI ARYGYLGALV GCFIFAMGNR PQGSPWKYKA AIYFFALLTT YMLVAAVLCT
780 VQAIKNINSP IFAKMVVSLI STYGIYVISS FLALDPWHIF TCFIQYVLFS PITDLLLLKL
840 ISMFHDLSWG TKGSDATQAS DLGAVSGVGK HVEVELVTAQ QDIDIAYQDA LDNIRLRGSK
900 VDSAESEPKK EQSEQAQKDT YANFRTNVSI AIMLVQKKRD DAKS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
526639
Janbon G.,Ormerod K.L.,Paulet D.,Byrnes E.J. III,Yadav V.,Chatterjee G.,Mullapudi N.,Hon C.-C.,Billmyre R.B.,Brunel F.,Bahn Y.-S.,Chen W.,Chen Y.,Chow E.W.L.,Coppee J.-Y.,Floyd-Averette A.,Gaillardin C.,Gerik K.J.,Goldberg J.,Gonzalez-Hilarion S.,Gujja S.,Hamlin J.L.,Hsueh Y.-P.,Ianiri G.,Jones S.,Kodira C.D.,Kozubowski L.,Lam W.,Marra M.,Mesner L.D.,Mieczkowski P.A.,Moyrand F.,Nielsen K.,Proux C.,Rossignol T.,Schein J.E.,Sun S.,Wollschlaeger C.,Wood I.A.,Zeng Q.,Neuveglise C.,Newlon C.S.,Perfect J.R.,Lodge J.K.,Idnurm A.,Stajich J.E.,Kronstad J.W.,Sanyal K.,Heitman J.,Fraser J.A.,Cuomo C.A.,Dietrich F.S.
Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.
PLoS Genet.
10
0-0
2014
526640
Banks I.R.,Specht C.A.,Donlin M.J.,Gerik K.J.,Levitz S.M.,Lodge J.K.
A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans.
Eukaryot. Cell
4
1902-1912
2005
526641
Park H.S.,Chow E.W.,Fu C.,Soderblom E.J.,Moseley M.A.,Heitman J.,Cardenas M.E.
Calcineurin Targets Involved in Stress Survival and Fungal Virulence.
PLoS Pathog.
12
0-0
2016
526642
Rodrigues J.,Ramos C.L.,Frases S.,Godinho R.M.D.C.,Fonseca F.L.,Rodrigues M.L.
Lack of chitin synthase genes impacts capsular architecture and cellular physiology in Cryptococcus neoformans.
Cell Surf.
2
14-23
2018
526643
Pianalto K.M.,Billmyre R.B.,Telzrow C.L.,Alspaugh J.A.
Roles for Stress Response and Cell Wall Biosynthesis Pathways in Caspofungin Tolerance in Cryptococcus neoformans.
Genetics
213
213-227
2019
