Sequence of C82X2_PAPSO
EC Number:1.14.14.163
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(S)-1-hydroxy-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 = (13S,14R)-1,13-dihydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O
Other sequences found for EC No. 1.14.14.163
General information:
Sequence
0 MKSLMMNKLL FLQRITDSPS TTIISTFIVT IISIVFLYTV LLIRTTKNKQ KIAAPKASGA
60 WPFIGHLKLF MKQDTQFYRT LGTMSDKYGS VFTLRLGNQA ILVVSNWEMV KECFTTNDKS
120 FSNRPSTLST KYMLNDTNSV VFSPYGTYWR EMRKILVQKL LISNQRSEAL KNLKTKEIDN
180 SFVKLNDLCN NDVSGGGTKV RMDEWLADMM FNIIARITFG YQSGGGDAPG ASTTSKNVER
240 YKKTLDEMFV VLATRFAVSD IFPSLEFIDR LRGLVKDMKI LGDELNSIAG CFIEEHRQKR
300 RESLSSLLSL SNESVGDEQD FIDVLLSIMD QSRLPGDDPD FIIKIMILEA FAGGTDSLSA
360 TLTWVLSLLL NHPNVLKRAR EEIDRHVENG KQVEVSDIPK LGYIDAIIKE TMRLYPVGAL
420 SERYTTEECE VGRFNVPAGT RLLVNIWKIH RDPSVWENPS DFQPERFLCS DKVGVDLYGQ
480 NYELIPFGAG RRVCPAIVSS LQTMHYALAR LIQGYEMKSA SLDGKVNMEE MIAMSCHKMS
540 PLEVIISPRE PRRS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
521881
Winzer T.,Gazda V.,He Z.,Kaminski F.,Kern M.,Larson T.R.,Li Y.,Meade F.,Teodor R.,Vaistij F.E.,Walker C.,Bowser T.A.,Graham I.A.
A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine.
Science
336
1704-1708
2012
521882
Dang T.T.,Chen X.,Facchini P.J.
Acetylation serves as a protective group in noscapine biosynthesis in opium poppy.
Nat. Chem. Biol.
11
104-106
2015
521883
Li Y.,Smolke C.D.
Engineering biosynthesis of the anticancer alkaloid noscapine in yeast.
Nat. Commun.
7
12137-12137
2016
521884
Li Y.,Li S.,Thodey K.,Trenchard I.,Cravens A.,Smolke C.D.
Complete biosynthesis of noscapine and halogenated alkaloids in yeast.
Proc. Natl. Acad. Sci. U.S.A.
115
0-0
2018
