EC Number   |
Protein Variants |
Reference |
|---|
   7.2.2.3 | D893A |
mutant with no significant Na+/K+ ATPase activity |
655506 |
| 7.2.2.3 | D893E |
mutant with no significant Na+/K+ ATPase activity |
655506 |
| 7.2.2.3 | D893R |
mutant with no significant Na+/K+ ATPase activity |
655506 |
| 7.2.2.3 | E139D |
the E139D mutant of the NtpK subunit loses tolerance to sodium but not to lithium at pH 10. The mutant enzyme retains relatively high specific activity and affinity for the lithium ion compared to the sodium ion. Vmax values of the mutant enzyme are reduced to approximately 34% of that of the wild type enzyme |
-, 719727 |
| 7.2.2.3 | G896I |
mutant with no significant Na+/K+ ATPase activity |
655506 |
| 7.2.2.3 | G896R |
mutant with no significant Na+/K+ ATPase activity |
655506 |
| 7.2.2.3 | S894D |
mutant with similar Na+/K+ ATPase activity as the wild-type enzyme |
655506 |
| 7.2.2.3 | S894I |
mutant with similar Na+/K+ ATPase activity as the wild-type enzyme |
655506 |
| 7.2.2.3 | T418N |
the mutant shows a lower level of inhibition by cipargamin compared to the wild type enzyme |
-, 748229 |
| 7.2.2.3 | T418N/P990R |
the mutant shows a lower level of inhibition by cipargamin compared to the wild type enzyme |
-, 748229 |
