EC Number   |
Protein Variants |
Reference |
|---|
   7.2.2.21 | C298A/C300A |
site-directed mutation of the CXC motif abolishes copper resistance but not cadmium resistance |
-, 698831 |
| 7.2.2.21 | C311A/C312A |
site-directed mutation of the CC motif abolishes cadmium resistance yet retains the ability to confer copper resistance |
-, 698831 |
| 7.2.2.21 | C354A |
transmembrane segment 6, participation in Cd2+ binding, inactive in transport of Cd2+, no ATPase activity |
669493 |
| 7.2.2.21 | C356A |
transmembrane segment 6, participation in Cd2+ binding, inactive in transport of Cd2+ |
669493 |
| 7.2.2.21 | D398A |
no enzymic activity |
667395 |
| 7.2.2.21 | D692A |
transmembrane segment 8, participation in Cd2+ binding, inactive in transport of Cd2+, no ATPase activity |
669493 |
| 7.2.2.21 | E164A |
transmembrane segment 4, reduced ATPase activity |
669493 |
| 7.2.2.21 | G970R |
naturally occurring missense mutation presented in a number of yeast laboratory strains, loss of function, mutation is not found in wild type strains |
687681 |
| 7.2.2.21 | M149A |
transmembrane segment 3, participation in Cd2+ binding, reduced ATPase activity |
669493 |
| 7.2.2.21 | more |
construction of a C-terminal fragment that contains heavy metal-binding domains |
657072 |
