EC Number   |
Protein Variants |
Reference |
|---|
    6.3.4.16 | A1378T |
the carbamoyl-phosphate synthetase deficiency-causing mutation greatly decreases enzyme activity |
727610 |
| 6.3.4.16 | A438P |
inactive |
727610 |
| 6.3.4.16 | Al38P |
the carbamoyl-phosphate synthetase deficiency-causing mutation greatly decreases enzyme activity |
727610 |
| 6.3.4.16 | C1327A |
the mutant shows reduced activity compared to the wild-type enzyme, the mutation significantly alters activity at the domain C ATP site, binding of N-acetylglutamate is affected, overview |
693247 |
| 6.3.4.16 | C1337A |
the mutant shows reduced activity compared to the wild-type enzyme, the mutation significantly alters activity at the domain C ATP site, binding of N-acetylglutamate is affected, overview |
693247 |
| 6.3.4.16 | D265A |
no carbamoyl phosphate synthesis |
-, 652334 |
| 6.3.4.16 | D265E |
about 10% of the specific acitivity of the wild-type enzyme |
652334 |
| 6.3.4.16 | D265N |
about 10% of the specific acitivity of the wild-type enzyme |
-, 652334 |
| 6.3.4.16 | D810A |
no carbamoyl phosphate synthesis |
652334 |
| 6.3.4.16 | D810E |
no carbamoyl phosphate synthesis |
652334 |
