EC Number   |
Protein Variants |
Reference |
|---|
   5.6.1.8 | D412A |
mutation in loop3, cardiomyopathy loop, involved in actin binding |
689744 |
| 5.6.1.8 | F547A |
mutation in loop 1, a hydrophobic triplet of residues, involved in actin binding |
689744 |
| 5.6.1.8 | I407A |
mutation in loop3, cardiomyopathy loop, involved in actin binding |
689744 |
| 5.6.1.8 | I499C |
plus cysteine-light mutations C49S, C312Y, C470I, C599L, C678Y, rescues growth of cells in suspension similarly to wild type, minimal implications on actin binding, ATP-induced actin release, actin-activated ATPase activity |
656005 |
| 5.6.1.8 | I499C/R738C |
plus cysteine-light mutations C49S, C312Y, C470I, C599L, C678Y, rescues growth of cells in suspension similarly to wild type, even after disulfide-induced crosslinking of mutated residues just minimal implications on actin binding, ATP-induced actin release, actin-activated ATPase activity |
656005 |
| 5.6.1.8 | K652A |
mutation in loop 2, involved in actin binding |
689744 |
| 5.6.1.8 | K652A/K653A |
double mutation in loop 2, involved in actin binding |
689744 |
| 5.6.1.8 | K653A |
mutation in loop 2, involved in actin binding |
689744 |
| 5.6.1.8 | more |
enzyme deletion mutant, no growth of cells in suspension |
656005 |
| 5.6.1.8 | more |
myosin loop 2 replaced by rabbit skeletal or smooth muscle loop 2 |
246976 |
