EC Number   |
Protein Variants |
Reference |
|---|
   5.6.1.6 | A196C |
[2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant |
750275 |
| 5.6.1.6 | A252C |
[2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant |
750275 |
| 5.6.1.6 | A299C |
site-directed mutagenesis, the engineered cysteine reacts with intracellular 2-sulfonatoethyl methanethiosulfonate |
733359 |
| 5.6.1.6 | A326C |
site-directed mutagenesis, the substituted cysteine does not respond to neither internal nor external 2-sulfonatoethyl methanethiosulfonate and is inaccessible to channel-permeant thiol-specific reagent [Au(CN)2]- |
733359 |
| 5.6.1.6 | A367C |
[2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant |
750275 |
| 5.6.1.6 | A462F |
site-directed mutagenesis, the mutation abolishes nucleotide interaction with ATP-binding site 1, the mutant exhibits a low, ATP-dependent open probability due to a reduced opening rate with a normal burst duration. The A462F mutation interfers with processing and trafficking to the cell membrane |
734231 |
| 5.6.1.6 | D1152H |
mutation in the CFTR gene causing cystic fibrosis |
699175 |
| 5.6.1.6 | D1370N |
site-directed mutagenesis of a conserved residue in the Walker B motif of ATP-binding site 2, the mutation abolishes P1,P5-di(adenosine-5') pentaphosphate, Ap5A, inhibition of current |
734231 |
| 5.6.1.6 | D572N |
site-directed mutagenesis of a conserved residue in the Walker B motif of ATP-binding site 1, the mutation does not abolish P1,P5-di(adenosine-5') pentaphosphate, Ap5A, inhibition of current |
734231 |
| 5.6.1.6 | D572N |
the mutation disrupts the interaction of ATP with ATP-binding site 1 |
751395 |
