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EC Number	Protein Variants	Commentary	Reference
4.99.1.3	C259S	site-directed mutagenesis	-, 652468
4.99.1.3	C262S	site-directed mutagenesis	-, 652468
4.99.1.3	E184L	mutation in metal binding site, about 3fold increase in activity	-, 747658
4.99.1.3	E184L/H216L	mutation in metal binding site, strong decrease in activity	747658
4.99.1.3	H127A	inactive	730419
4.99.1.3	H12A	wild type enzyme	682635
4.99.1.3	H145A/H207A	site-directed mutagenesis	644511
4.99.1.3	H154L	mutation in metal binding site. Mutant has negligible activity	-, 747658
4.99.1.3	H154L/E184L	mutation in metal binding site, negligible activity	-, 747658
4.99.1.3	H154L/E184L/H216L	mutation in metal binding site. Mutant has negligible activity	747658

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Release 2023.1 (January 2023)