EC Number |
Protein Variants |
Reference |
---|
4.2.1.8 | E185D |
kcat decreased compared to wild-type, Km decreased compared to wild-type |
730286 |
4.2.1.8 | E185G |
kcat increased compared to wild-type, Km slightly decreased compared to wild-type |
730286 |
4.2.1.8 | E186D |
kcat decreased compared to wild-type, Km decreased compared to wild-type |
730286 |
4.2.1.8 | E186G |
kcat and Km increased compared to wild-type |
730286 |
4.2.1.8 | E63A/S64A |
inactive mutant |
730286 |
4.2.1.8 | H311A |
the activity of H311A is only 2.4% that of the native wild type enzyme |
704307 |
4.2.1.8 | H32G |
kcat and Km increased compared to wild-type |
730286 |
4.2.1.8 | N103A/D109A |
kcat decreased compared to wild-type, Km slightly decreased compared to wild-type |
730286 |
4.2.1.8 | N36G |
kcat increased compared to wild-type, Km slightly decreased compared to wild-type |
730286 |
4.2.1.8 | W110F |
inactive mutant |
730286 |