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EC Number
Protein Variants
Commentary
Reference
4.2.1.18
A240V
site-directed mutagenesis, nucleotide exchange C719T
679737
4.2.1.18
E112Q/E132Q/R69A
protein is insoluble
-
,
747539
4.2.1.18
E112Q/E132Q/R69A/Y231F
protein is insoluble
-
,
747539
4.2.1.18
E112Q/E132Q/Y231F
protein is insoluble
-
,
747539
4.2.1.18
E138A
inactive mutant enzyme
-
,
664032
4.2.1.18
E138D
the ratio of turnover number to KM-value is 9fold lower than the wild-type ratio
-
,
664032
4.2.1.18
E138Q
the ratio of turnover number to KM-value is 3600fold lower than the wild-type ratio
-
,
664032
4.2.1.18
G118E
no activity with crotonyl-CoA, methylcrotonyl-CoA and methylglutaconyl-CoA
-
,
664032
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