EC Number   |
Protein Variants |
Reference |
|---|
    4.2.1.113 | F16A |
site-directed mutagenesis, the mutant enzyme activity is reduced compared to the wild-type enzyme |
729241 |
| 4.2.1.113 | F39A |
site-directed mutagenesis, the mutant enzyme activity is reduced compared to the wild-type enzyme |
729241 |
| 4.2.1.113 | F51A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
729216 |
| 4.2.1.113 | F51Y |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
729216 |
| 4.2.1.113 | G16P/V17F/V18R/L19T/R20S/D21F/R22G/R23T/L24QL48A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
729216 |
| 4.2.1.113 | G254A |
site-directed mutagenesis, the mutant enzyme activity is reduced compared to the wild-type enzyme |
729241 |
| 4.2.1.113 | G254T |
site-directed mutagenesis, the mutant enzyme activity is reduced compared to the wild-type enzyme |
729241 |
| 4.2.1.113 | G288A |
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme, G288A introduces a steric clash with the substrate, reducing kcat/KM over 500fold |
729216 |
| 4.2.1.113 | G295A |
site-directed mutagenesis, the mutant enzyme activity is reduced compared to the wild-type enzyme |
729241 |
| 4.2.1.113 | I265A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
729216 |
