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EC Number
Protein Variants
Commentary
Reference
4.1.3.30
C123A
no enzyme activity
651720
4.1.3.30
C123S
the mutation has a significant effect on its mechanism in terms of both rate and stereochemistry
748460
4.1.3.30
D58A
no enzyme activity
651720
4.1.3.30
H125A
decreased kcat
651720
4.1.3.30
K121A
decreased kcat
651720
4.1.3.30
L521F
L521 contributes to substrate specificity
-
,
714846
4.1.3.30
L521F/S523T
L521 and S523 contribute to substrate specificity
-
,
714846
4.1.3.30
more
TgPrpB gene disrupture by double homologous gene replacement in RH tachyzoites. The enzyme-deficient prpb-ko mutant is complemented by expression of wild-type myc-tagged TgPrpB
728336
4.1.3.30
R122K
decreased kcat
651720
4.1.3.30
S523T
S523 contributes to substrate specificity
-
,
714846
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