EC Number |
Protein Variants |
Reference |
---|
4.1.2.43 | H134A |
the mutation abolishes HPS activity |
-, 716871 |
4.1.2.43 | H134D |
the mutation abolishes HPS activity |
-, 716871 |
4.1.2.43 | H134K |
the mutation abolishes HPS activity |
-, 716871 |
4.1.2.43 | H134N |
the mutation abolishes HPS activity |
-, 716871 |
4.1.2.43 | H134S |
the mutation abolishes HPS activity |
716871 |
4.1.2.43 | K61A |
the mutant exhibits 50-90% of the activity of the wild type enzyme |
-, 716871 |
4.1.2.43 | K61D |
the mutant exhibits 50-90% of the activity of the wild type enzyme |
716871 |
4.1.2.43 | K61H |
the mutant exhibits 50-90% of the activity of the wild type enzyme |
716871 |
4.1.2.43 | K61S |
the mutant exhibits 50-90% of the activity of the wild type enzyme |
716871 |
4.1.2.43 | more |
in order to improve the rate of vanillin degradation by Burkholderia cepacia TM1, the hps and phi genes from Methylomonas aminofaciens 77a are heterologously expressed in strain TM1, the transformant strain constitutively produces active 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase enzymes and the degradation of vanillic acid and the growth yield are significantly improved |
-, 701850 |