EC Number   |
Protein Variants |
Reference |
|---|
   3.6.4.7 | D662N |
Walker-motif mutant: mutant shows a lower level of targeting to EGFP-Pex26p as compared to wild-type |
721086 |
| 3.6.4.7 | D803N |
Walker-motif mutant: mutant is transported to peroxisomes by EGFP-Pex26p to the same level as wild-type |
721086 |
| 3.6.4.7 | D940N |
Walker-motif mutant: mutant shows a normal or slightly increased level of targeting to EGFP-Pex26p as compared to wild-type |
721086 |
| 3.6.4.7 | G843D |
most frequently identified mutation in patients with infantile Refsum disease, protein is rapidly degraded in vivo at 37°C, interaction with Pex6 protein at 50% of wild-type level |
654490 |
| 3.6.4.7 | G843D |
the mutation of the PEX1 component causes a mild form of peroxisome biogenesis disorder |
755919 |
| 3.6.4.7 | K174A |
mutant, binds with approximately the same affinity and specificity as the wild-type protein |
668578 |
| 3.6.4.7 | K476E |
Walker-motif mutant: mutant shows a lower level of targeting to EGFP-Pex26p as compared to wild-type |
721086 |
| 3.6.4.7 | K605E |
Walker-motif mutant: mutant are significantly reduced in translocation to EGFP-Pex26p as compared to wild-type |
721086 |
| 3.6.4.7 | K750E |
Walker-motif mutant: mutant shows a lower level of targeting to EGFP-Pex26p as compared to wild-type |
721086 |
| 3.6.4.7 | K887E |
Walker-motif mutant: mutant are significantly reduced in translocation to EGFP-Pex26p as compared to wild-type |
721086 |
