EC Number   |
Protein Variants |
Reference |
|---|
   3.6.1.45 | F463L |
enhanced 5' nucleotidase activity, UDP-sugar hydrolase activity not determined |
675821 |
| 3.6.1.45 | more |
carboxyterminal deletion which abolishes the 5' nucleotidase activity and deletion of the signal peptide |
651739 |
| 3.6.1.45 | more |
deletion of the signal peptide, identical to the mature periplasmic enzyme, except for the presence of an N-terminal methionine residue, expressed in Escherichia coli 5A-1 |
651739 |
| 3.6.1.45 | more |
ushA knockouts are unable to grow on AMP as the only carbon source and are significantly delayed or impaired in their growth on other purine nucleotides. Growth on nonadenine purine nucleotides is made possible by an acid phosphatase encoded by the aphA gene, which at neutral pH acts as an efficient 5'-nucleotidase of purine nucleotides, except AMP. Double knockouts in ushA and aphA do not grow on nucleotides AMP |
698591 |
| 3.6.1.45 | S139Y |
occurs naturally, loss of 5' nucleotidase activity, UDP-sugar hydrolase activity not determined |
675821 |
| 3.6.1.45 | S139Y/F463Y |
loss of 5' nucleotidase activity, UDP-sugar hydrolase activity not determined |
675821 |
