EC Number   |
Protein Variants |
Reference |
|---|
    3.5.4.3 | A386S |
4.8fold decrease in kcat/Km value |
752789 |
| 3.5.4.3 | D327L |
no residual activity |
752789 |
| 3.5.4.3 | D330A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
689944 |
| 3.5.4.3 | E143X |
the mutation results in a complete loss of activity |
733339 |
| 3.5.4.3 | E240D |
no residual activity |
752789 |
| 3.5.4.3 | E79X |
the mutation results in a complete loss of activity |
733339 |
| 3.5.4.3 | F210A |
20fold decrease in kcat/Km value |
752789 |
| 3.5.4.3 | H237R |
no residual activity |
752789 |
| 3.5.4.3 | H240A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
689944 |
| 3.5.4.3 | H279A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
689944 |
