EC Number   |
Protein Variants |
Reference |
|---|
    3.5.4.25 | C396S |
site-directed mutagenesis, |
716533 |
| 3.5.4.25 | C54S |
site-directed mutagenesis, mutation results in proteins devoid of bound zinc and unable to release formate from the imidazole ring of GTP or from the intermediate analogue 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-triphosphate, however, the mutant enzyme is still capable to release diphosphate from GTP and from the formamide-type intermediate analogue |
655443 |
| 3.5.4.25 | C65S |
site-directed mutagenesis, mutation results in proteins devoid of bound zinc and unable to release formate from the imidazole ring of GTP or from the intermediate analogue 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-triphosphate, however, the mutant enzyme is still capable to release diphosphate from GTP and from the formamide-type intermediate analogue |
655443 |
| 3.5.4.25 | C67S |
site-directed mutagenesis, mutation results in proteins devoid of bound zinc and unable to release formate from the imidazole ring of GTP or from the intermediate analogue 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-triphosphate, however, the mutant enzyme is still capable to release diphosphate from GTP and from the formamide-type intermediate analogue |
655443 |
| 3.5.4.25 | D127A |
about 10fold less efficient than the wild-type protein |
696250 |
| 3.5.4.25 | E154D |
site-directed mutagenesis, |
716533 |
| 3.5.4.25 | G209D |
about 10fold less efficient than the wild-type protein |
696250 |
| 3.5.4.25 | M120A |
generated by site-directed mutagenesis |
696250 |
| 3.5.4.25 | M120C |
generated by site-directed mutagenesis |
696250 |
| 3.5.4.25 | M120D |
generated by site-directed mutagenesis |
696250 |
